Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

16.7%

2 terminated/withdrawn out of 12 trials

Success Rate

83.3%

-3.2% vs industry average

Late-Stage Pipeline

33%

4 trials in Phase 3/4

Results Transparency

90%

9 of 10 completed trials have results

Key Signals

9 with results

Enrollment Performance

Analytics

Phase 2
5(45.5%)
Phase 4
3(27.3%)
N/A
2(18.2%)
Phase 3
1(9.1%)
11Total
Phase 2(5)
Phase 4(3)
N/A(2)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT02842957Not ApplicableCompleted

An Intensive Lifestyle Intervention Program in CKD (Move to Health 2)

Role: collaborator

NCT04903717Not ApplicableCompleted

Pragmatic Trial Of Alerts for Use of Mineralocorticoid Receptor Antagonists

Role: collaborator

NCT03597035Phase 4Terminated

Mineralocorticoid Receptor Antagonism Clinical Evaluation in Atherosclerosis Add-On

Role: collaborator

NCT01810939Phase 3Completed

A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL)

Role: lead

NCT01371747Phase 2Completed

Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN)

Role: lead

NCT00868439Phase 2Completed

Evaluation of Patiromer in Heart Failure Patients

Role: lead

NCT03071263Phase 2Completed

Spironolactone With Patiromer in the Treatment of Resistant Hypertension in Chronic Kidney Disease

Role: lead

NCT02033317Phase 2Terminated

An Open-Label, Multiple Dose Study to Evaluate the Pharmacology, Safety, and Tolerability of Patiromer in Participants on Hemodialysis

Role: lead

NCT01130597Phase 2Completed

Evaluation of Patiromer Titration in Heart Failure Patients With Chronic Kidney Disease

Role: lead

NCT02694744Phase 4Completed

Patiromer With or Without Food for the Treatment of Hyperkalemia

Role: lead

NCT02933450Phase 4Completed

Relypsa For ED Acute Hyperkalemia Control and Reduction (REDUCE)

Role: collaborator

NCT02823626Completed

High-dose Aldosterone Antagonist for Acute Decompensated Heart Failure

Role: collaborator

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