Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

5.9%

1 terminated/withdrawn out of 17 trials

Success Rate

92.9%

+6.4% vs industry average

Late-Stage Pipeline

24%

4 trials in Phase 3/4

Results Transparency

38%

5 of 13 completed trials have results

Key Signals

1 recruiting5 with results

Enrollment Performance

Analytics

Phase 1
7(43.8%)
Phase 2
4(25.0%)
Phase 3
4(25.0%)
Early Phase 1
1(6.3%)
16Total
Phase 1(7)
Phase 2(4)
Phase 3(4)
Early Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (17)

Showing 17 of 17 trials
NCT07280156Phase 2Recruiting

A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)

Role: lead

NCT05745727Phase 1Completed

A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid Levels

Role: lead

NCT01981720Phase 1Completed

Extension Study of PRX-102 for up to 60 Months

Role: lead

NCT03018730Phase 3Completed

Safety and Efficacy of PRX-102 in Patients With Fabry Disease Currently Treated With REPLAGAL® (Agalsidase Alfa)

Role: lead

NCT02795676Phase 3Completed

Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal Function

Role: lead

NCT01678898Phase 1Completed

Dose-ranging Study of PRX-102 in Adult Fabry Disease Patients

Role: lead

NCT03180840Phase 3Completed

Safety, Efficacy, & PK of PRX-102 in Patients With Fabry Disease Administered Intravenously Every 4 Weeks

Role: lead

NCT05186324Completed

Fabry Patient's Experience Of PegunigaLsidasE Alfa Monthly Infusion

Role: collaborator

NCT02921620Phase 3Withdrawn

Study to Evaluate the Safety and EffIcacy of PRX-102 on Gastrointestinal Symptoms in Naïve Fabry Disease

Role: lead

NCT02722122Phase 2Unknown

Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Exploratory Efficacy Parameters of AIR DNase™in Patients With Cystic Fibrosis Previously Treated With Pulmozyme®

Role: lead

NCT02768974Phase 2Unknown

Open Label Study to Assess Safety, PK and Explore Efficacy of OPRX-106 in Patients With Active Mild to Moderate Ulcerative Colitis

Role: lead

NCT02107846Phase 2Completed

An Open-Label, Dose Escalation Study to Evaluate the Safety and the Pharmacokinetics of Oral PRX-112

Role: lead

NCT02605590Phase 1Completed

Safety, Tolerability and Pharmacokinetics Study of AIR DNAse Administered by Inhalation to Healthy Adult Volunteers

Role: lead

NCT02107833Phase 1Completed

Study to Evaluate the Safety and Pharmacokinetics of Oral OPRX-106 (TNFR-Fc Fusion Protein) in Healthy Volunteers

Role: lead

NCT01747980Phase 1Completed

Safety and Pharmacokinetics of Oral PRX-112 in Gaucher Disease Patients

Role: lead

NCT01093859Early Phase 1Completed

An Exploratory Phase 1 Microdose Study of PRX-105

Role: lead

NCT00258778Phase 1Completed

Phase I Single Dose-Escalation Safety Study of Human Glucocerebrosidase (prGCD)

Role: lead

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