Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

7.1%

1 terminated/withdrawn out of 14 trials

Success Rate

90.9%

+4.4% vs industry average

Late-Stage Pipeline

14%

2 trials in Phase 3/4

Results Transparency

20%

2 of 10 completed trials have results

Key Signals

1 recruiting2 with results

Enrollment Performance

Analytics

Phase 2
7(50.0%)
Phase 1
5(35.7%)
Phase 3
2(14.3%)
14Total
Phase 2(7)
Phase 1(5)
Phase 3(2)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT07153146Phase 1Recruiting

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PN-881 in Healthy Subjects.

Role: lead

NCT02895100Phase 2Terminated

Safety and Efficacy Study of PTG-100 in the Treatment of Moderate to Severe Ulcerative Colitis

Role: lead

NCT04202965Phase 2Completed

PTG-300 in Subjects With Hereditary Hemochromatosis

Role: lead

NCT05210790Phase 3Active Not Recruiting

A Phase 3 Study of Rusfertide in Patients With Polycythemia Vera

Role: lead

NCT04057040Phase 2Completed

Hepcidin Mimetic in Patients With Polycythemia Vera (REVIVE)

Role: lead

NCT06033586Phase 3Active Not Recruiting

Study to Evaluate the Long-term Safety of Rusfertide (PTG-300) in Subjects With Polycythemia Vera

Role: lead

NCT04767802Phase 2Completed

PTG-300 in Patients With Polycythemia Vera and Elevated Hematocrit

Role: lead

NCT04504383Phase 2Completed

PN-943 in Adults With Moderate to Severe Active Ulcerative Colitis (UC)

Role: lead

NCT04819620Phase 1Completed

Pharmacokinetics of PN-232 in Healthy Volunteers

Role: lead

NCT04524221Phase 1Completed

PTG-100 for Patients With Celiac Disease

Role: collaborator

NCT04621630Phase 1Completed

Pharmacokinetics of PN-235 in Healthy Volunteers

Role: lead

NCT04516382Phase 1Completed

Pharmacokinetics and Pharmacodynamics of Different PTG-300 Regimens in Healthy Volunteers

Role: lead

NCT04054921Phase 2Completed

Safety Study for Beta Thalassemia Subjects on PTG-300

Role: lead

NCT03802201Phase 2Completed

Study of PTG-300 in Non-Transfusion Dependent and Transfusion-Dependent Beta-Thalassemia Subjects With Chronic Anemia

Role: lead

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