Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 15/100

Failure Rate

7.1%

1 terminated/withdrawn out of 14 trials

Success Rate

91.7%

+5.2% vs industry average

Late-Stage Pipeline

21%

3 trials in Phase 3/4

Results Transparency

100%

11 of 11 completed trials have results

Key Signals

2 recruiting11 with results

Enrollment Performance

Analytics

Phase 1
8(61.5%)
Phase 3
3(23.1%)
Phase 2
2(15.4%)
13Total
Phase 1(8)
Phase 3(3)
Phase 2(2)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT06851559Phase 2Recruiting

A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks

Role: lead

NCT06831344Phase 1Completed

A Study to Evaluate Two Vonoprazan Orally Disintegrating Tablet Formulations Administered Without Water or Mixed With Water and Administered Via a Syringe Relative to the Vonoprazan Tablet in Healthy Participants

Role: lead

NCT06660342Recruiting

A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring

Role: lead

NCT05343364Phase 1Completed

A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of Vonoprazan in Adolescents With Symptomatic Gastroesophageal Reflux Disease

Role: lead

NCT06391177Phase 1Completed

A Study to Evaluate Vonoprazan Concentrations in Breast Milk of Healthy Lactating Women Receiving Vonoprazan 20 mg Once Daily or Vonoprazan 20 mg Twice Daily

Role: lead

NCT06106022Phase 1Completed

A Study to Evaluate Vonoprazan in Children Who Have Symptomatic Gastroesophageal Reflux Disease

Role: lead

NCT05366738Phase 1Completed

A Study to Determine the Bioavailability of Vonoprazan Sprinkle Capsules on Pudding or on Applesauce Relative to a Vonoprazan Tablet in Healthy Participants

Role: lead

NCT05195528Phase 3Completed

A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo for Relief of Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease (NERD)

Role: lead

NCT04729101Phase 1Completed

Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Vonoprazan and Lansoprazole in Healthy Participants

Role: lead

NCT04545944Phase 1Completed

Evaluation of Effect of Vonoprazan on Midazolam Pharmacokinetics in Healthy Participants

Role: lead

NCT04799158Phase 2Completed

A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease

Role: lead

NCT04124926Phase 3Completed

Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Erosive Esophagitis

Role: lead

NCT04167670Phase 3Completed

Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Helicobacter Pylori Infection

Role: lead

NCT04558216Phase 1Withdrawn

Evaluation of Effect of Rifampin on the Pharmacokinetics of Vonoprazan in Healthy Participants

Role: lead

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