Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

16.7%

4 terminated/withdrawn out of 24 trials

Success Rate

76.5%

-10.0% vs industry average

Late-Stage Pipeline

21%

5 trials in Phase 3/4

Results Transparency

62%

8 of 13 completed trials have results

Key Signals

1 recruiting8 with results

Enrollment Performance

Analytics

Phase 2
16(72.7%)
Phase 3
5(22.7%)
Phase 1
1(4.5%)
22Total
Phase 2(16)
Phase 3(5)
Phase 1(1)

Activity Timeline

Global Presence

Loading network data...

Clinical Trials (24)

Showing 20 of 24 trials
NCT05438407Phase 3Active Not Recruiting

Pediatric Patients Aged 4 to 11 Years With APDS

Role: lead

NCT05145283Phase 2Completed

Recombinant Human C1 Esterase Inhibitor (Conestat Alfa) in the Prevention of Acute Ischemic Cerebral and Renal Events After Transcatheter Aortic Valve Implantation

Role: collaborator

NCT02859727Phase 2Terminated

Extension to the Study of Efficacy of CDZ173 in Patients With APDS/PASLI

Role: lead

NCT06549114Phase 2Active Not Recruiting

Leniolisib for Immune Dysregulation in PIDs

Role: lead

NCT06990529Phase 2Recruiting

Long-term Safety and Efficacy of Leniolisib in PIDs With Immune Dysregulation

Role: lead

NCT06897358Phase 2Active Not Recruiting

Leniolisib for Immune Dysregulation in CVID

Role: lead

NCT05693129Phase 3Active Not Recruiting

Pediatric Patients Aged 1 to 6 Years With APDS

Role: lead

NCT01397864Completed

C1 Inhibitor Registry in the Treatment of Hereditary Angioedema (HAE) Attacks

Role: lead

NCT03697187Completed

Patient Registry to Evaluate the Real-world Safety of Ruconest®

Role: lead

NCT04912141Phase 2Terminated

Prevention of Acute Kidney Injury in Patients With NSTEMI

Role: lead

NCT01359969Phase 2Completed

Safety of Ruconest in 2-13 Year Old Hereditary Angioedema (HAE) Patients

Role: lead

NCT04530136Phase 2Completed

Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19

Role: lead

NCT06249997Phase 3Unknown

An Open-Label Study to Assess the Safety & Efficacy of Leniolisib in Japanese Patients With APDS

Role: lead

NCT04414631Phase 2Terminated

Conestat Alfa in the Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19

Role: collaborator

NCT03791476Phase 1Unknown

RUCONEST® as a Therapeutic Strategy to Reduce the Incidence of Delayed Graft Function

Role: collaborator

NCT02869347Phase 2Completed

Recombinant Human C1 Esterase Inhibitor in the Prevention of Contrast-induced Nephropathy in High-risk Subjects

Role: collaborator

NCT00851409Phase 2Completed

A Study of the Safety and Immunogenicity of Repeated rhC1INH Administration

Role: lead

NCT02247739Phase 2Completed

A Phase 2 HAE Prophylaxis Study With Recombinant Human C1 Inhibitor

Role: lead

NCT01188564Phase 3Completed

Efficacy, Safety and Immunogenicity Study of Recombinant Human C1 Inhibitor for the Treatment of Acute HAE Attacks

Role: lead

NCT00261053Phase 2Completed

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema

Role: lead