Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

16.7%

19 terminated/withdrawn out of 114 trials

Success Rate

80.8%

-5.7% vs industry average

Late-Stage Pipeline

19%

22 trials in Phase 3/4

Results Transparency

75%

60 of 80 completed trials have results

Key Signals

3 recruiting60 with results15 terminated4 withdrawn

Enrollment Performance

Analytics

Phase 1
47(42.3%)
Phase 2
40(36.0%)
Phase 3
22(19.8%)
Early Phase 1
2(1.8%)
111Total
Phase 1(47)
Phase 2(40)
Phase 3(22)
Early Phase 1(2)

Activity Timeline

Global Presence

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Clinical Trials (114)

Showing 20 of 114 trials
NCT05963074Phase 2Recruiting

A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia

Role: collaborator

NCT03462719Phase 3Active Not Recruiting

A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Role: collaborator

NCT01804686Phase 3Recruiting

A Long-term Extension Study of PCI-32765 (Ibrutinib)

Role: collaborator

NCT04450173Phase 2Active Not Recruiting

Obinutuzumab, Ibrutinib, and Venetoclax for the Treatment of Previously Untreated Stage II-IV Follicular Lymphoma

Role: collaborator

NCT01479842Phase 1Active Not Recruiting

Rituxan/Bendamustine/PCI-32765 in Relapsed DLBCL, MCL, or Indolent Non-Hodgkin's Lymphoma

Role: collaborator

NCT02947347Phase 3Completed

Study of Ibrutinib and Rituximab in Treatment Naïve Follicular Lymphoma

Role: lead

NCT03359460Phase 1Completed

Ibrutinib and Lenalidomide in Treating Patients With Myelodysplastic Syndrome

Role: collaborator

NCT03198026Phase 2Active Not Recruiting

Obinutuzumab and Ibrutinib as Front Line Therapy in Treating Patients With Indolent Non-Hodgkin's Lymphomas

Role: collaborator

NCT02315326Phase 1Completed

Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Patients With Newly Diagnosed or Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)

Role: collaborator

NCT03703167Phase 1Completed

Ibrutinib With Rituximab and Lenalidomide for Patients With Recurrent/Refractory Primary or Secondary Central Nervous System Lymphoma (PCNSL/SCNSL)

Role: collaborator

NCT02518555Phase 2Active Not Recruiting

Ibrutinib as an Immune Modulating Agent for Patients With Asymptomatic, High-risk CLL/SLL Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Role: collaborator

NCT03702725Phase 1Completed

Study of Ibrutinib in Combination With Revlimid/Dexamethasone in Relapsed/Refractory Multiple Myeloma

Role: collaborator

NCT02251548Phase 2Active Not Recruiting

A Phase II Study of Ibrutinib Plus FCR in Previously Untreated, Younger Patients With Chronic Lymphocytic Leukemia

Role: collaborator

NCT03790332Phase 1Completed

Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD)

Role: lead

NCT05564052Phase 2Completed

A Study of Ibrutinib With Rituximab in Relapsed or Refractory Mantle Cell Lymphoma

Role: collaborator

NCT02315768Phase 1Completed

Ibrutinib in Combination With GA101 (Obinutuzumab) in Previously Untreated Chronic Lymphocytic Leukemia (CLL) Patients.

Role: collaborator

NCT03207555Phase 2Completed

Ibrutinib as Early Therapy in Chronic Lymphocytic Leukemia (CLL)

Role: collaborator

NCT04273139Phase 2Active Not Recruiting

Ibrutinib + Venetoclax in Untreated WM

Role: collaborator

NCT01027910Phase 1Completed

PCI-24781 in Combination With Doxorubicin to Treat Sarcoma

Role: collaborator

NCT04212013Phase 3Active Not Recruiting

A Study of Ibrutinib With Rituximab in People With Untreated Marginal Zone Lymphoma

Role: collaborator