Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

3.4%

1 terminated/withdrawn out of 29 trials

Success Rate

96.6%

+10.0% vs industry average

Late-Stage Pipeline

17%

5 trials in Phase 3/4

Results Transparency

21%

6 of 28 completed trials have results

Key Signals

6 with results

Enrollment Performance

Analytics

Phase 2
14(53.8%)
Phase 1
7(26.9%)
Phase 3
5(19.2%)
26Total
Phase 2(14)
Phase 1(7)
Phase 3(5)

Activity Timeline

Global Presence

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Clinical Trials (29)

Showing 20 of 29 trials
NCT00357916Phase 1Completed

Study to Determine the Sensitizing Potential of PEP005 Topical Gel in Healthy Volunteers Using a Repeat Insult Patch Test Design

Role: lead

NCT01325688Phase 2Completed

PEP005 Gel - Evaluation of the Safety and Efficacy of Ingenol Mebutate Gel on a Superficial Basal Cell Carcinoma on the Trunk or Extremities

Role: lead

NCT00432185Phase 2Completed

To Determine the Maximum Tolerated Dose Level (MTD) of PEP005 Topical Gel in Patients With sBCC

Role: lead

NCT00375739Phase 2Completed

Study to Determine the Safety of PEP005 0.025% and 0.05% Topical Gel in Patients With Actinic Keratoses

Role: lead

NCT00546611Phase 1Withdrawn

The Purpose of This Study is to Determine Whether Topical Application of PEP005 is Safe for the Treatment of Common Wart(s)

Role: lead

NCT00427050Phase 2Completed

A Study to Determine the Optimal Tolerated Regime and Safety of PEP005 Topical Gel

Role: lead

NCT01302925Phase 1Completed

PEP005 Gel - Evaluation of Local Tolerability After Exposure to Ingenol Mebutate Gel Followed by Hand Washing in Healthy Subjects

Role: lead

NCT00659893Phase 1Completed

Safety and Toleration of PEP005 Topical Gel When Applied to a Treatment Area of up to 100cm2

Role: lead

NCT00850681Phase 1Completed

A Study to Evaluate the Photoallergic Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers

Role: lead

NCT00850811Phase 1Completed

A Study to Evaluate the Photoirritation Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers

Role: lead

NCT00917306Phase 3Completed

A Multi-center Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on Non-head Locations (Trunk and Extremities)

Role: lead

NCT00700063Phase 2Completed

A Multicenter Study to Evaluate the Safety and Efficacy of PEP005 Topical Gel When Used to Treat Actinic Keratoses on the Head (Face or Scalp)

Role: lead

NCT00916006Phase 3Completed

A Multi-center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp)

Role: lead

NCT00544297Phase 2Completed

A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses on the Top of the Hand

Role: lead

NCT00989313Completed

A Long Term Follow up Study of Patients Who Have Complete Clearance of Their Actinic Keratosis (AK) Lesions at the Day 57 Visit in the PEP005-028 Study

Role: lead

NCT00953732Completed

A Long Term Follow up Study of Patients Who Have Completed the PEP005-016 or PEP005-025 Studies

Role: lead

NCT00952783Completed

A Long Term Follow up Study of Patients Who Have Completed the PEP005-020 Study

Role: lead

NCT00107965Phase 2Completed

Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Actinic Keratoses

Role: lead

NCT00239135Phase 2Completed

Study to Determine the Maximum Tolerated Dose and Safety of PEP005 Topical Gel

Role: lead

NCT00852137Phase 2Completed

A Study to Evaluate the Pharmacokinetics of PEP005 (Ingenol Mebutate) Gel, 0.05%, When Applied in a Maximal Use Setting to the Dorsal Aspect of the Forearm in Patients With Actinic Keratosis

Role: lead