Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

16.7%

2 terminated/withdrawn out of 12 trials

Success Rate

80.0%

-6.5% vs industry average

Late-Stage Pipeline

25%

3 trials in Phase 3/4

Results Transparency

50%

4 of 8 completed trials have results

Key Signals

4 with results

Enrollment Performance

Analytics

Phase 2
9(75.0%)
Phase 3
3(25.0%)
12Total
Phase 2(9)
Phase 3(3)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT04318145Phase 2Terminated

Study to Evaluate Sex Differences in the Acute Effects of PL-3994 in Heart Failure Subjects

Role: lead

NCT06565611Phase 2Active Not Recruiting

A Phase 2 Study Evaluating the Co-Administration of Bremelanotide With Tirzepatide for the Treatment of Obesity

Role: lead

NCT05466890Phase 2Active Not Recruiting

Phase 2a to Evaluate PL-8177 in Subjects with Active Ulcerative Colitis (UC)

Role: lead

NCT05201170Phase 3Completed

A Phase 3, Multi-Center Study Evaluating PL9643 in Patients with Dry Eye

Role: lead

NCT05709444Phase 2Completed

A Phase IIb, Multicenter, Open-Label, Prospective Study of Bremelanotide in Diabetic Kidney Disease

Role: lead

NCT02333071Phase 3Completed

1. Study to Evaluate the Efficacy/Safety of Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder

Role: lead

NCT02338960Phase 3Completed

2. Study to Evaluate the Efficacy/Safety of Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder

Role: lead

NCT04268069Phase 2Completed

Efficacy and Safety of PL9643 Ophthalmic Solution in Subjects With Dry Eye

Role: collaborator

NCT01382719Phase 2Completed

Bremelanotide in Premenopausal Women With Female Sexual Arousal Disorder and/or Hypoactive Sexual Desire Disorder

Role: lead

NCT01304628Phase 2Withdrawn

Cross-Over Study of Subcutaneous Study Drug for the Treatment of Patients With Mild to Moderate Asthma

Role: lead

NCT00686803Phase 2Completed

Safety Study of Subcutaneously Administered PL-3994 in Subjects With Controlled Hypertension

Role: lead

NCT00425256Phase 2Completed

Evaluate the Safety and Efficacy of Bremelanotide in Women With Female Sexual Arousal Disorder (FSAD)

Role: lead

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