Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

8.3%

1 terminated/withdrawn out of 12 trials

Success Rate

87.5%

+1.0% vs industry average

Late-Stage Pipeline

0 trials in Phase 3/4

Results Transparency

86%

6 of 7 completed trials have results

Key Signals

2 recruiting6 with results

Enrollment Performance

Analytics

Phase 2

5(41.7%)

Phase 1

5(41.7%)

N/A

2(16.7%)

12Total

Phase 2(5)

Phase 1(5)

N/A(2)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials

NCT07506239Not ApplicableRecruiting

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

Role: collaborator

NCT07447076Phase 2Not Yet Recruiting

Study of Novel Therapies for Young People With Recurrent/Progressive Atypical Teratoid Rhabdoid Tumor (ATRT)

Role: collaborator

NCT03429803Phase 1Completed

DAY101 In Gliomas and Other Tumors

Role: collaborator

NCT01734512Phase 2Completed

PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children

Role: collaborator

NCT03739372Not ApplicableActive Not Recruiting

Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

Role: collaborator

NCT03231306Phase 2Completed

Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas

Role: collaborator

NCT04775485Phase 2Recruiting

A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

Role: collaborator

NCT03690869Phase 1Terminated

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Role: collaborator

NCT02960230Phase 1Completed

H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas

Role: collaborator

NCT03579602Phase 2Completed

Study of Tozuleristide and the Canvas Imaging System in Pediatric Subjects With CNS Tumors Undergoing Surgery

Role: collaborator

NCT03086616Phase 1Completed

CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With Diffuse Intrinsic Pontine Glioma (DIPG) (PNOC 009)

Role: collaborator

NCT03566199Phase 1Completed

MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma

Role: collaborator

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