Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

27.0%

10 terminated/withdrawn out of 37 trials

Success Rate

65.5%

-21.0% vs industry average

Late-Stage Pipeline

32%

12 trials in Phase 3/4

Results Transparency

32%

6 of 19 completed trials have results

Key Signals

1 recruiting6 with results8 terminated

Enrollment Performance

Analytics

N/A

18(54.5%)

Phase 3

8(24.2%)

Phase 4

4(12.1%)

Phase 1

3(9.1%)

33Total

N/A(18)

Phase 3(8)

Phase 4(4)

Phase 1(3)

Activity Timeline

Global Presence

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Clinical Trials (37)

Showing 20 of 37 trials

NCT06000410Phase 3Completed

A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

Role: lead

NCT04636229Phase 3Completed

Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

Role: lead

NCT06618612Not ApplicableRecruiting

A Study to Evaluate the Efficacy of a Purified Native Type 1 Collagen Extracellular Matrix With Polyhexamethylene Biguanide Antimicrobial (PCMP) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers

Role: lead

NCT01623882Withdrawn

Clinical Evaluation of the Combined Use of Apligraf® and the SNaP® Pressure Wound Therapy System

Role: collaborator

NCT03502824Not ApplicableTerminated

PuraPly® AM Plus the Standard of Care to Standard of Care Alone for the Management of Stage II-IV Pressure Ulcers.

Role: lead

NCT04901013Not ApplicableUnknown

Clinical Study Of Affinity Versus SOC In The Management Of VLUs

Role: lead

NCT02808234Not ApplicableUnknown

Study of Nucel for One and Two Level Lumbar Interbody Fusion

Role: lead

NCT03855514Not ApplicableUnknown

Randomized Clinical Study Assessing NuShield Versus Standard of Care in Diabetic Foot Ulcers

Role: lead

NCT02982226Not ApplicableUnknown

ReNu™ vs. Corticosteroids for the Treatment of Plantar Fasciitis

Role: collaborator

NCT02880592Not ApplicableCompleted

Effect of Fresh Amniotic Membrane in the Treatment of Diabetic Foot Ulcers

Role: lead

NCT03205436Not ApplicableCompleted

Affinity Prospective Diabetic Foot Trial Crossover Group

Role: lead

NCT02837484Not ApplicableUnknown

NuTech Affinity™ for the Treatment of Chondral Defects

Role: collaborator

NCT03036878Not ApplicableTerminated

ReNu™ Marrow Stimulation Augmentation

Role: collaborator

NCT02318511Not ApplicableCompleted

An Investigation of ReNu™ Knee Injection in Patients With Osteoarthritis

Role: collaborator

NCT02023372Not ApplicableCompleted

Efficacy Study of NuCel® in Patients Undergoing Fusion of the Lumbar Spine

Role: collaborator

NCT03828916Not ApplicableUnknown

NuShield in Surgical Peroneal Tendon Repair

Role: collaborator

NCT03063099Not ApplicableCompleted

ReNu™ Injection to Treat Hip Osteoarthritis Study

Role: collaborator

NCT03286452Completed

The RESPOND Registry

Role: lead

NCT02461641Not ApplicableCompleted

NuShield/Affinity for the Treatment of Neuropathic Diabetic Foot Ulcers

Role: collaborator

NCT00909870Phase 3Completed

Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers

Role: lead