Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

4.8%

9 terminated/withdrawn out of 189 trials

Success Rate

93.3%

+6.8% vs industry average

Late-Stage Pipeline

30%

56 trials in Phase 3/4

Results Transparency

41%

52 of 126 completed trials have results

Key Signals

14 recruiting52 with results8 terminated

Enrollment Performance

Analytics

Phase 1
67(38.7%)
Phase 3
53(30.6%)
Phase 2
50(28.9%)
Phase 4
3(1.7%)
173Total
Phase 1(67)
Phase 3(53)
Phase 2(50)
Phase 4(3)

Activity Timeline

Global Presence

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Clinical Trials (189)

Showing 20 of 189 trials
NCT07198087Phase 1Active Not Recruiting

A Study to Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy Participants

Role: lead

NCT03661320Phase 3Active Not Recruiting

A Study to Compare Chemotherapy Alone Versus Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Therapy After Surgery With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle Invasive Bladder Cancer

Role: collaborator

NCT05696548Phase 2Active Not Recruiting

Nivolumab Plus Lenvatinib Against Anaplastic Thyroid Cancer (NAVIGATION)

Role: collaborator

NCT05923866Phase 2Active Not Recruiting

A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy

Role: lead

NCT06752603Phase 2Active Not Recruiting

A Clinical Study of ONO-1110 in Patients With Hunner Type Interstitial Cystitis

Role: lead

NCT04947319Phase 2Active Not Recruiting

Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study)

Role: lead

NCT06948448Phase 2Recruiting

A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

Role: lead

NCT06752590Phase 2Active Not Recruiting

A Clinical Study of ONO-1110 in Patients With Fibromyalgia

Role: lead

NCT06525246Phase 1Completed

Study of ONO-7475 in Combination With Osimertinib in EGFR Gene Mutation-positive Non-small Cell Lung Cancer

Role: lead

NCT06256328Phase 2Active Not Recruiting

A Study to Investigate the Efficacy and Safety of ONO-4578 in Combination With Nivolumab and Chemotherapy in Chemotherapy-naïve Participants With HER2-negative Unresectable Advanced or Recurrent Gastric Cancer (Including Esophagogastric Junction Cancer)

Role: lead

NCT06622941Phase 2Recruiting

Study to ONO-4538 in Patients With Rhabdoid Tumor

Role: lead

NCT07104032Phase 3Recruiting

IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

Role: lead

NCT03036098Phase 3Active Not Recruiting

Study of Nivolumab in Combination With Ipilimumab or Standard of Care Chemotherapy Compared to the Standard of Care Chemotherapy Alone in Treatment of Participants With Untreated Inoperable or Metastatic Urothelial Cancer

Role: collaborator

NCT06708416Phase 2Active Not Recruiting

A Study of ONO-1110 in Patients With Postherpetic Neuralgia

Role: lead

NCT07429266Phase 3Not Yet Recruiting

A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)

Role: lead

NCT06805565Phase 2Active Not Recruiting

A Study of ONO-1110 in Patients With Social Anxiety Disorder

Role: lead

NCT06792136Phase 2Active Not Recruiting

A Study of ONO-1110 in Patients With Major Depressive Disorder

Role: lead

NCT03143153Phase 3Completed

A Study to Evaluate Efficacy in Subjects With Esophageal Cancer Treated With Nivolumab and Ipilimumab or Nivolumab Combined With Fluorouracil Plus Cisplatin Versus Fluorouracil Plus Cisplatin

Role: collaborator

NCT05079282Phase 1Recruiting

Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

Role: lead

NCT06936943Phase 2Recruiting

ONO-4538 Study in Patients With Richter's Transformation

Role: lead