Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

31.3%

20 terminated/withdrawn out of 64 trials

Success Rate

51.2%

-35.3% vs industry average

Late-Stage Pipeline

8%

5 trials in Phase 3/4

Results Transparency

76%

16 of 21 completed trials have results

Key Signals

9 recruiting16 with results15 terminated5 withdrawn

Enrollment Performance

Analytics

N/A
18(31.0%)
Phase 2
16(27.6%)
Phase 1
15(25.9%)
Phase 3
4(6.9%)
Early Phase 1
4(6.9%)
Phase 4
1(1.7%)
58Total
N/A(18)
Phase 2(16)
Phase 1(15)
Phase 3(4)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (64)

Showing 20 of 64 trials
NCT06390059Phase 2Completed

EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma

Role: lead

NCT05341349Phase 1Terminated

Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases

Role: collaborator

NCT06906900Phase 1Recruiting

A Phase I Study of the NovoTTF-200M and Novo TTF-200A Systems for the Treatment of Refractory Spinal Metastasis

Role: collaborator

NCT05764954Phase 1Recruiting

A Study of Tumor-Treating Fields (TTFields) in People With Lung Adenocarcinoma

Role: collaborator

NCT04471844Not ApplicableCompleted

Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM

Role: lead

NCT05086497Not ApplicableRecruiting

WBSI Guided Personalized Delivery of TTFields

Role: collaborator

NCT03033992Not ApplicableActive Not Recruiting

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

Role: collaborator

NCT04605913Phase 1Recruiting

Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC

Role: collaborator

NCT06552000Not ApplicableNot Yet Recruiting

Pre-operative Tumor Treating Fields in Patients With Resectable Lung Cancer

Role: collaborator

NCT03450850Not ApplicableCompleted

Study Of NOVOTTF-200A In Bevacizumab-Naive Subjects With Recurrent Grade III Malignant Astrocytoma

Role: collaborator

NCT06222138Not ApplicableRecruiting

Study of Biologic Tumor and Plasma Biomarkers of Response to TTFields in Patients Treated for Newly Diagnosed Glioblastoma

Role: collaborator

NCT03405792Phase 2Active Not Recruiting

Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP)

Role: collaborator

NCT03377491Phase 3Completed

Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel (PANOVA-3)

Role: lead

NCT05679674Not ApplicableRecruiting

Stereotactic Body Radiation and Tumor Treating Fields for Locally Advanced Pancreas Cancer

Role: collaborator

NCT04221503Phase 2Active Not Recruiting

Niraparib/TTFields in GBM

Role: collaborator

NCT04129515Phase 1Withdrawn

NovoTTF-200A + Pembrolizumab In Melanoma Brain Metastasis

Role: collaborator

NCT04474353Phase 1Completed

Study of Tumor Treating Fields With Hypofractionated Chemoradiotherapy in Newly Diagnosed Glioblastoma

Role: collaborator

NCT03223103Phase 1Active Not Recruiting

Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma

Role: collaborator

NCT05538806Recruiting

TTFields in General Routine Clinical Care in Patients With Pleural Mesothelioma Study

Role: lead

NCT05004025Phase 1Completed

Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma

Role: collaborator