Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 5/100

Failure Rate

9.6%

22 terminated/withdrawn out of 228 trials

Late-Stage Pipeline

43%

99 trials in Phase 3/4

Results Transparency

114%

33 of 29 completed trials have results

Key Signals

66 recruiting33 with results21 terminated

Enrollment reporting

Analytics

Phase 3
88(38.6%)
Phase 2
60(26.3%)
Phase 1
43(18.9%)
Phase 1/2
25(11.0%)
Phase 4
11(4.8%)
Phase 2/3
1(0.4%)
228Total
Phase 3(88)
Phase 2(60)
Phase 1(43)
Phase 1/2(25)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (228)

Showing 20 of 228 trials
NCT03960840Phase 1/2Active Not Recruiting

Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL

Role: lead

NCT07288359Phase 1/2Recruiting

Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

Role: lead

NCT07604571Phase 1Recruiting

Study of IEV407 as Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer

Role: lead

NCT07217067Phase 2Recruiting

A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation

Role: lead

NCT07737743Phase 2Recruiting

A Phase 2a/b Study to Assess the Efficacy, Safety and Tolerability of DDY391 in Participants With Sjögren's Disease

Role: lead

NCT05360446Phase 3Active Not Recruiting

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

Role: lead

NCT06846281Phase 3Recruiting

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

Role: lead

NCT07357727Phase 3Recruiting

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

Role: lead

NCT07468071Phase 1/2Active Not Recruiting

Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments

Role: lead

NCT07570979Phase 1Recruiting

A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer

Role: lead

NCT03340506Phase 4Recruiting

Dabrafenib and/or Trametinib Rollover Study

Role: lead

NCT06247995Phase 1/2Active Not Recruiting

A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

Role: lead

NCT05358249Phase 1/2Terminated

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

Role: lead

NCT05838768Phase 1Active Not Recruiting

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

Role: lead

NCT05849298Phase 2Active Not Recruiting

A Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPC

Role: lead

NCT05939414Phase 3Recruiting

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

Role: lead

NCT07094516Phase 2Active Not Recruiting

A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

Role: lead

NCT07146906Phase 2Recruiting

A Study to Assess the Effects of Zigakibart on IgA Nephropathy.

Role: lead

NCT05544929Phase 1Active Not Recruiting

A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

Role: lead

NCT06531499Phase 1Active Not Recruiting

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

Role: lead