Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 50/100

Failure Rate

14.3%

2 terminated/withdrawn out of 14 trials

Success Rate

83.3%

-3.2% vs industry average

Late-Stage Pipeline

21%

3 trials in Phase 3/4

Results Transparency

20%

2 of 10 completed trials have results

Key Signals

2 with results

Enrollment Performance

Analytics

Phase 1
8(57.1%)
Phase 2
3(21.4%)
Phase 3
3(21.4%)
14Total
Phase 1(8)
Phase 2(3)
Phase 3(3)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT02726386Phase 2Active Not Recruiting

A Long Term Safety Study of ND0612 Administered as a Continuous SC Infusion in Advanced Parkinson's Disease

Role: lead

NCT04006210Phase 3Active Not Recruiting

Efficacy, Safety and Tolerability Study of ND0612 vs. Oral Immediate Release Levodopa/Carbidopa (IR-LD/CD) in Subjects With Parkinson's Disease Experiencing Motor Fluctuations

Role: lead

NCT01725802Phase 1Completed

A Safety, Tolerability, and Plasma Concentration Study of Levodopa/Carbidopa Subcutaneous Solution (ND0612) in Parkinson's Disease (PD) Patients

Role: lead

NCT02096601Phase 1Completed

A Safety, Tolerability, and Pharmacokinetic Study of ND0612 Delivered as a Continuous Subcutaneous in Parkinson's Disease Patients

Role: lead

NCT02604914Phase 1Completed

A Sequential Two-Part, Open-Label Study in Healthy Male and Female Subjects

Role: lead

NCT01883505Phase 2Completed

A Phase 2a Study Followed to Evaluate the Safety, Tolerability and Levodopa Pharmacokinetics in Levodopa-treated Parkinson's Disease Patients Receiving ND0612

Role: lead

NCT01486628Phase 1Completed

Study of Subcutaneous Continuous Administration of Levodopa/Carbidopa Solution (ND0612) in Healthy Volunteers

Role: lead

NCT02577523Phase 2Completed

A Clinical Study of Efficacy, Safety, Tolerability and PK of ND0612H in Subjects With Advanced Parkinson's Disease

Role: lead

NCT02782481Phase 3Withdrawn

A Clinical Study Investigating the Efficacy, Tolerability, and Safety of Continuous Subcutaneous ND0612 Infusion Given as Adjunct Treatment to Oral Levodopa in Patients With Parkinson's Disease With Motor Fluctuations

Role: lead

NCT01174355Phase 1Completed

A Study of ND0801 in Attention Deficit/Hyperactivity Disorder (ADHD)

Role: lead

NCT03462043Phase 3Withdrawn

A Study in Patients With Advanced Parkinson's Disease to Assess the Relative Bioavailability of Levodopa Administered as ND0612 Subcutaneous Infusion Versus Levodopa Administered as Carbidopa-Levodopa Enteral Suspension

Role: lead

NCT02486432Phase 1Completed

A Single Period Investigation to Assess the Tolerability of Healthy Subjects to Oral Sinemet® (Levodopa/Carbidopa)

Role: lead

NCT01229332Phase 1Completed

A Safety, Tolerability and Pharmacokinetic Study of ND0611 on the Top of Different Oral Dosage Forms of Levodopa/Carbidopa in Parkinson's Disease Patients

Role: lead

NCT01103011Phase 1Completed

Safety, Tolerability and Pharmacokinetic Profile of Levodopa Administered With Continuous Administration of ND0611

Role: lead

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