Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

14.3%

2 terminated/withdrawn out of 14 trials

Success Rate

84.6%

-1.9% vs industry average

Late-Stage Pipeline

7%

1 trials in Phase 3/4

Results Transparency

18%

2 of 11 completed trials have results

Key Signals

1 recruiting2 with results

Enrollment Performance

Analytics

Phase 2
10(71.4%)
Phase 1
3(21.4%)
Phase 3
1(7.1%)
14Total
Phase 2(10)
Phase 1(3)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT07281079Phase 3Recruiting

A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome

Role: lead

NCT05025332Phase 2Completed

An Open-Label Study of Oral NNZ-2591 in Pitt Hopkins Syndrome (PTHS-001)

Role: lead

NCT05025241Phase 2Completed

An Open-Label Study of Oral NNZ-2591 in Phelan-McDermid Syndrome (PMS-001)

Role: lead

NCT05011851Phase 2Completed

An Open-Label Study of the Safety, Tolerability, and Pharmacokinetics of Oral NNZ-2591 in Angelman Syndrome

Role: lead

NCT05879614Phase 2Withdrawn

An Open-Label Study of Oral NNZ-2591 in Prader-Willi Syndrome (PWS-001)

Role: lead

NCT04379869Phase 1Completed

To Evaluate the Safety, Tolerability and Pharmacokinetics of Oral NNZ-2591 in Healthy Volunteers

Role: lead

NCT02715115Phase 2Completed

A Safety Study of NNZ-2566 in Pediatric Rett Syndrome

Role: lead

NCT01703533Phase 2Completed

A Safety Study of NNZ-2566 in Patients With Rett Syndrome

Role: lead

NCT01366820Phase 2Completed

Study of NNZ-2566 in Patients With Traumatic Brain Injury Under EFIC

Role: lead

NCT02100150Phase 2Terminated

A Safety and Efficacy Study of NNZ-2566 in Patients With Mild Traumatic Brain Injury (mTBI)

Role: lead

NCT01894958Phase 2Completed

A Safety Study of NNZ-2566 in Patients With Fragile X Syndrome

Role: lead

NCT00805818Phase 2Completed

Study of NNZ-2566 in Patients With Traumatic Brain Injury

Role: lead

NCT00961779Phase 1Completed

Safety Study of NNZ-2566 in Healthy Female Subjects

Role: lead

NCT01420042Phase 1Completed

Safety Study of NNZ-2566 in Healthy Subjects, Following Oral Administration

Role: lead

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