Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

42.9%

9 terminated/withdrawn out of 21 trials

Success Rate

52.6%

-33.9% vs industry average

Late-Stage Pipeline

33%

7 trials in Phase 3/4

Results Transparency

130%

13 of 10 completed trials have results

Key Signals

13 with results7 terminated

Enrollment Performance

Analytics

Phase 3
7(36.8%)
Phase 2
6(31.6%)
Phase 1
6(31.6%)
19Total
Phase 3(7)
Phase 2(6)
Phase 1(6)

Activity Timeline

Global Presence

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Clinical Trials (21)

Showing 20 of 21 trials
NCT03157167Phase 1Completed

An Evaluation of Tc 99m Tilmanocept by Intravenous (IV) and Subcutaneous (SC) Injection in Kaposi Sarcoma (KS)

Role: lead

NCT05246280Phase 3Terminated

Tc 99m Tilmanocept Imaging for Early Prediction of Anti-TNFα Therapy Response in Moderate to Severe Active RA

Role: lead

NCT04947137Phase 2Completed

Development of a Normative Database for Rheumatoid Arthritis (RA) Imaging With Tc99m Tilmanocept

Role: lead

NCT04078191Phase 2Terminated

Comparison of Tc 99m Tilmanocept Imaging With IHC Analysis of CD206 Expression in Synovial Tissue of Subjects With RA

Role: lead

NCT03332940Phase 1Terminated

Safety Evaluation of IV Tc 99m Tilmanocept and Comparison of Imaging With Sulfur Colloid in Subjects With and Without NASH

Role: lead

NCT01812213Phase 2Terminated

Beta-Amyloid Imaging With [18F]NAV4694 PET in Predicting Progression to AD in Subjects MCI

Role: lead

NCT03938636Phase 2Completed

Evaluation of the Precision and Sensitivity of Tilmanocept Uptake Value (TUV) on Tc 99m Tilmanocept Planar Imaging

Role: lead

NCT02542371Completed

Use of 99mTc Tilmanocept for Imaging Arterial Inflammation

Role: collaborator

NCT02865434Phase 1Completed

Evaluating Safety of Escalating Doses of Tilmanocept by IV Injection and SPECT Imaging in Subjects With and Without RA

Role: lead

NCT03029988Phase 1Terminated

An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases.

Role: lead

NCT02683421Phase 1Completed

Evaluation of SC Injected Tc 99m Tilmanocept Localization in Active RA Subjects by SPECT and SPECT/CT Imaging

Role: lead

NCT02065232Completed

Sentinel Lymph Node Mapping Post-Injection Site Pain

Role: collaborator

NCT03241446Phase 1Withdrawn

Pharmacokinetics and Dosimetry of Tc 99m Tilmanocept Following a Single Intravenous Dose Administration in Male and Female Subjects Diagnosed With Rheumatoid Arthritis (RA)

Role: lead

NCT01950455Phase 3Terminated

Evaluation of the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the Diagnosis of Parkinsonian Syndromes

Role: lead

NCT01950468Phase 3Withdrawn

A Cross-Over, Multi-Center Trial to Evaluate the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the Diagnosis of Parkinsonian Syndromes

Role: lead

NCT01886820Phase 3Unknown

A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of [18F]NAV4694 PET for Detection of Cerebral Beta-Amyloid When Compared With Postmortem Histopathology

Role: lead

NCT02201420Phase 2Completed

Evaluation of Tc 99m Tilmanocept Localization in Primary Cutaneous Kaposi's Sarcoma and Lymphatic Drainage by SPECT/CT

Role: lead

NCT01680588Phase 2Unknown

Efficacy and Safety of the PET Imaging Agent [18F]NAV4694 in Subjects With Probable Alzheimer's Disease

Role: lead

NCT00911326Phase 3Terminated

Evaluation of Sentinel Lymph Nodes in Head and Neck Squamous Cell Carcinoma

Role: lead

NCT01106040Phase 3Completed

Breast and Melanoma Trial With Lymphoseek to Identify Lymph Nodes

Role: lead