Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

4.8%

1 terminated/withdrawn out of 21 trials

Success Rate

94.4%

+7.9% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

65%

11 of 17 completed trials have results

Key Signals

11 with results

Enrollment Performance

Analytics

Phase 2
13(65.0%)
Phase 1
7(35.0%)
20Total
Phase 2(13)
Phase 1(7)

Activity Timeline

Global Presence

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Clinical Trials (21)

Showing 20 of 21 trials
NCT06743776Unknown

Scalable Expanded Access With Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS

Role: collaborator

NCT04057898Phase 2Active Not Recruiting

Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS

Role: lead

NCT05464784Phase 2Active Not Recruiting

MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia

Role: lead

NCT02503657Phase 2Completed

Safety, Tolerability, and Efficacy of MN-001 (Tipelukast) in Patients With Idiopathic Pulmonary Fibrosis

Role: lead

NCT03782415Phase 1Completed

Study to Evaluate Ibudilast and TMZ Combo Treatment in Newly Diagnosed and Recurrent Glioblastoma

Role: lead

NCT03594435Phase 2Completed

Ibudilast for the Treatment of Alcohol Use Disorder

Role: collaborator

NCT04429555Phase 2Completed

Efficacy, Safety, Tolerability, and Biomarkers of Ibudilast (MN-166) in Patients Hospitalized With COVID-19 at Risk for ARDS

Role: lead

NCT02714036Phase 1Completed

A Biomarker Study to Evaluate MN-166 in Subjects With Amyotrophic Literal Sclerosis (ALS)

Role: lead

NCT01217970Phase 1Completed

Safety Interaction Trial Ibudilast and Methamphetamine

Role: collaborator

NCT02681055Phase 2Completed

Open-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD Subjects

Role: lead

NCT02238626Phase 2Completed

Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS)

Role: lead

NCT01982942Phase 2Completed

Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis

Role: lead

NCT04054206Phase 1Completed

Relative Bioavailability of MN-166 (Ibudilast) in Extended Release Tablet vs. Intermediate-release Capsule in Healthy Volunteers

Role: lead

NCT03533387Phase 1Completed

Study of MN-166 (Ibudilast) Extended Release Tablet Formulations Compared With Capsules in Healthy Volunteers

Role: lead

NCT01740414Phase 2Completed

Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers

Role: collaborator

NCT01013142Phase 1Completed

Evaluate the Safety of MN-221 in Subjects With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Role: lead

NCT00838591Phase 2Completed

Study Evaluating the Safety and Efficacy of MN-221 as an Adjunct to Standard Therapy in Subjects Experiencing an Acute Exacerbation of Asthma

Role: lead

NCT01551316Phase 1Completed

Safety Study to Evaluate MN-221 in Chronic Obstructive Pulmonary Disease (COPD) Patients

Role: lead

NCT00295854Phase 2Completed

Phase II Study Efficacy and Safety of Two Dosing Regimens of MN-001 in Patients With Interstitial Cystitis

Role: lead

NCT00679263Phase 2Completed

Study Evaluating the Safety and Effects of MN-221 in Subjects With Moderate to Severe Asthma

Role: lead