Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 15/100

Failure Rate

8.3%

1 terminated/withdrawn out of 12 trials

Success Rate

87.5%

+1.0% vs industry average

Late-Stage Pipeline

42%

5 trials in Phase 3/4

Results Transparency

57%

4 of 7 completed trials have results

Key Signals

1 recruiting4 with results

Enrollment Performance

Analytics

Phase 3
4(33.3%)
Phase 2
4(33.3%)
Phase 1
3(25.0%)
Phase 4
1(8.3%)
12Total
Phase 3(4)
Phase 2(4)
Phase 1(3)
Phase 4(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT04311671Phase 3Completed

Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole

Role: lead

NCT03876262Phase 3Active Not Recruiting

Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis

Role: lead

NCT07172659Phase 2Not Yet Recruiting

Efficacy and Safety Study of Dovramilast in People With Leprosy Type 2 Reaction

Role: lead

NCT07145736Phase 4Recruiting

Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases

Role: collaborator

NCT07159373Phase 3Not Yet Recruiting

Better Options for Lymphatic Filariasis Treatment

Role: lead

NCT03962062Phase 1Completed

A Pharmacokinetic and Safety Study of Moxidectin to Identify an Optimal Dose for Treatment of Children 4 to 11 Years

Role: lead

NCT05875441Phase 2Completed

Efficacy and Safety Study of Moxidectin in Adults With Scabies

Role: lead

NCT03905265Phase 2Completed

Dose-finding Study of Moxidectin for Treatment of Scabies

Role: lead

NCT00300768Phase 2Completed

Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection

Role: lead

NCT03012828Phase 1Completed

Effect of a Single Oral Dose of Moxidectin on the Cardiac QT Interval of Healthy Volunteers

Role: lead

NCT01123915Phase 1Terminated

A Safety and Immunogenicity Study of 3 Doses of Opal Immunotherapy in HIV Infected People

Role: lead

NCT00790998Phase 3Completed

Study Comparing Moxidectin And Ivermectin In Subjects With Onchocerca Volvulus Infection

Role: lead

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