Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

25.0%

3 terminated/withdrawn out of 12 trials

Success Rate

70.0%

-16.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

114%

8 of 7 completed trials have results

Key Signals

1 recruiting8 with results

Enrollment Performance

Analytics

Phase 2
9(75.0%)
Phase 1
2(16.7%)
N/A
1(8.3%)
12Total
Phase 2(9)
Phase 1(2)
N/A(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT05406713Phase 2Active Not Recruiting

Pembrolizumab in Muscle-invasive Bladder Cancer

Role: lead

NCT06809140Phase 2Recruiting

Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

Role: lead

NCT03557918Phase 2Completed

Trial of Tremelimumab in Patients With Previously Treated Metastatic Urothelial Cancer

Role: lead

NCT03558087Phase 2Completed

Gemcitabine, Cisplatin, Plus Nivolumab in Patients With Muscle-invasive Bladder Cancer With Selective Bladder Sparing

Role: lead

NCT03451331Phase 2Completed

Gemcitabine + Carboplatin + Nivolumab Versus Gemcitabine + Oxaliplatin + Nivolumab in Cisplatin-ineligible Patients With Metastatic Urothelial Cancer

Role: lead

NCT01215136Phase 2Terminated

First-line Everolimus +/- Paclitaxel for Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma

Role: lead

NCT03448718Phase 2Completed

Trial of Olaparib in Patients With Metastatic Urothelial Cancer Harboring DNA Damage Response Gene Alterations

Role: lead

NCT03359239Phase 1Completed

Atezolizumab Given in Combination With a Personalized Vaccine in Patients With Urothelial Cancer

Role: lead

NCT02500121Phase 2Completed

Testing the PD-1 Inhibitor Pembrolizumab as Maintenance Therapy After Initial Chemotherapy in Metastatic Bladder Cancer

Role: lead

NCT01331824Phase 2Terminated

Trial of Amrubicin as Second-Line Therapy in Patients With Advanced/Metastatic Refractory Urothelial Carcinoma

Role: lead

NCT02376166Not ApplicableCompleted

Metformin for Rising PSA Remote Trial

Role: lead

NCT01496534Phase 1Terminated

Phase Ib Study of Gemcitabine Plus Cisplatin or Carboplatin Plus Dovitinib in Patients With Advanced Solid Tumors

Role: lead

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