Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

20.0%

3 terminated/withdrawn out of 15 trials

Success Rate

76.9%

-9.6% vs industry average

Late-Stage Pipeline

27%

4 trials in Phase 3/4

Results Transparency

20%

2 of 10 completed trials have results

Key Signals

2 with results

Enrollment Performance

Analytics

Phase 1
6(40.0%)
Phase 2
5(33.3%)
Phase 3
4(26.7%)
15Total
Phase 1(6)
Phase 2(5)
Phase 3(4)

Activity Timeline

Global Presence

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Clinical Trials (15)

Showing 15 of 15 trials
NCT02694393Phase 1Terminated

Inhaled Sodium Nitrite as an Antimicrobial for Cystic Fibrosis

Role: collaborator

NCT02646358Phase 1Completed

Study of the Effect of Renal Impairment on the Pharmacokinetics of Vepoloxamer

Role: lead

NCT02596477Phase 2Terminated

Evaluation of Vepoloxamer in Chronic Heart Failure

Role: lead

NCT01737814Phase 3Completed

Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC)

Role: lead

NCT02449616Phase 3Completed

Evaluation of Repeat Administration of Purified Poloxamer 188

Role: lead

NCT02093468Phase 2Terminated

Evaluation of MST-188 in Acute Lower Limb Ischemia

Role: lead

NCT01790087Phase 1Completed

ANX-188 Thorough QT/QTc Study in Healthy Volunteers

Role: lead

NCT00004408Phase 3Completed

Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease

Role: lead

NCT00432562Phase 1Completed

A Bioequivalence Study of Vinorelbine Tartrate Injectable Emulsion in Patients With Advanced Cancer.

Role: lead

NCT00663481Phase 1Completed

A Clinical Trial of CoFactor Formulations and Leucovorin Administered Intravenously in Healthy, Adult Subjects.

Role: lead

NCT00664170Phase 1Completed

A Bioequivalence Study of Docetaxel for Injectable Emulsion (ANX-514) in Patients With Advanced Cancer

Role: lead

NCT00235898Phase 2Completed

Clinical Trial in Patients With Metastatic Colorectal Cancer

Role: lead

NCT00434369Phase 2Unknown

5-Fluorouracil Combined With CoFactor (5-10 Methylenetetrahydrofolate) in Treating Advanced Breast Cancer Patients

Role: lead

NCT00081627Phase 2Completed

Clinical Trial in Patients With Metastatic Colorectal Cancer

Role: lead

NCT00337389Phase 3Unknown

Phase III Randomized Study of 5-FU, CoFactor, and Avastin vs. 5-FU, LV and Avastin for First-Line Colorectal Cancer.

Role: lead

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