Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

16.8%

31 terminated/withdrawn out of 184 trials

Success Rate

74.2%

-12.3% vs industry average

Late-Stage Pipeline

23%

42 trials in Phase 3/4

Results Transparency

8%

7 of 89 completed trials have results

Key Signals

21 recruiting7 with results25 terminated6 withdrawn

Enrollment Performance

Analytics

Phase 2
55(40.4%)
N/A
33(24.3%)
Phase 3
31(22.8%)
Phase 4
11(8.1%)
Phase 1
6(4.4%)
136Total
Phase 2(55)
N/A(33)
Phase 3(31)
Phase 4(11)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (184)

Showing 20 of 184 trials
NCT06158698Phase 3Recruiting

CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine

Role: collaborator

NCT05985122Not ApplicableActive Not Recruiting

New Analytic Tools for aHUS and C3G Diagnosis

Role: lead

NCT06594367Completed

A Possible Founding PKD2 Mutation Associated With Variable Phenotypes of ADPKD in Bergamo Province

Role: lead

NCT05996731Not ApplicableRecruiting

Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases

Role: lead

NCT06242327Recruiting

An Outcome Analysis of Primary Membranous Nephropathy

Role: lead

NCT04095156Recruiting

Autoreactive B Cells in Membranous Nephropathy

Role: lead

NCT06994468Not ApplicableCompleted

Effect of B-cell Depleting Therapies on PLA2R-specific B Cells in Patients With Membranous Nephropathy

Role: lead

NCT07428018Phase 2Not Yet Recruiting

Pragmatic Study to Optimize Neoadjuvant Treatment and Surgical De-escalation in HR+/HER2- Early Breast Cancer Using Oncotype DX and Abemaciclib

Role: lead

NCT04794127Phase 2Completed

Study on Trabectedin in Combination With Pioglitazone in Patients Myxoid Liposarcomas With Stable Disease After T Alone.

Role: lead

NCT07416942Not Yet Recruiting

Omics of Rituximab-resistance

Role: lead

NCT07233330Phase 2Not Yet Recruiting

Obinutuzumab in Adult Rituximab-Dependent Nephrotic Syndrome

Role: lead

NCT07318025Not ApplicableNot Yet Recruiting

AVF-MONITOR POC Proof-of-concept Study

Role: lead

NCT07331103Not ApplicableRecruiting

RESOLving INflammation Through Diet for Health (RESOLVIN)

Role: lead

NCT04113863Phase 2Terminated

Evaluation of ATRA Activity in Combination With Anastrozole in Pre-operative Phase of Operable Early Breast Cancer

Role: lead

NCT06680050Phase 2Recruiting

Phase II Study of Radiotherapy Followed by Durvalumab and Ceralasertib in Stage III NSCLC Patients With Thoracic Relapses +/- Oligometastases After PACIFIC Regimen

Role: lead

NCT04765709Phase 2Terminated

Durvalumab and Chemotherapy Induction Followed by Durvalumab and Radiotherapy in Large Volume Stage III NSCLC

Role: lead

NCT07270198Not ApplicableNot Yet Recruiting

Mechanisms Underlying SGLT2i Kidney Effect in DKD Progression

Role: lead

NCT05966051Completed

MuLtidimensional School-based and Family interVentions to Promote hEalthy and Sustainable LifestYle for the Childhood

Role: lead

NCT05805202Not ApplicableRecruiting

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy

Role: lead

NCT06126315Phase 2Recruiting

Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS

Role: lead