Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

7.4%

5 terminated/withdrawn out of 68 trials

Success Rate

91.8%

+5.3% vs industry average

Late-Stage Pipeline

29%

20 trials in Phase 3/4

Results Transparency

59%

33 of 56 completed trials have results

Key Signals

5 recruiting33 with results

Enrollment Performance

Analytics

Phase 1
28(41.8%)
Phase 3
20(29.9%)
Phase 2
18(26.9%)
Early Phase 1
1(1.5%)
67Total
Phase 1(28)
Phase 3(20)
Phase 2(18)
Early Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (68)

Showing 20 of 68 trials
NCT06217302Phase 3Recruiting

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Role: collaborator

NCT06481891Phase 3Recruiting

A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy

Role: lead

NCT04662281Phase 2Completed

Efficacy and Safety of LX9211 in Participants With Postherpetic Neuralgia

Role: lead

NCT03910387Phase 2Completed

Telotristat Ethyl to Promote Weight Stability in Patients With Advanced Stage Pancreatic Cancer

Role: collaborator

NCT06203002Phase 2Completed

A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)

Role: lead

NCT07211802Phase 3Not Yet Recruiting

CKM For Safe Use of SGLT2i in Type 1 Diabetes

Role: collaborator

NCT06933056Early Phase 1Recruiting

Comparison of Antiplatelet Effects of Sotagliflozin to FDA-approved Antiplatelet Drugs

Role: collaborator

NCT06435156Phase 2Recruiting

Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes

Role: collaborator

NCT04455633Phase 2Completed

Efficacy, Safety, and PK of LX9211 in Participants With Diabetic Peripheral Neuropathic Pain

Role: lead

NCT05696366Phase 1Recruiting

Combination Adjunctive Therapy to Address Multiple Metabolic Imbalances in Type 1 Diabetes

Role: collaborator

NCT03521934Phase 3Terminated

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

Role: lead

NCT03315143Phase 3Terminated

Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk

Role: lead

NCT03242252Phase 3Completed

Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control

Role: lead

NCT03386344Phase 3Terminated

Efficacy and Bone Safety of Sotagliflozin 400 and 200 mg Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control

Role: lead

NCT03242018Phase 3Completed

A Study to Evaluate Safety and Effects of Sotagliflozin 400 and 200 mg on Glucose Control in Participants With Type 2 Diabetes, Severe Impairment of Kidney Function and Inadequate Blood Sugar Control

Role: lead

NCT02926937Phase 3Completed

Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus Not Currently Treated With Antidiabetic Therapy

Role: lead

NCT03351478Phase 3Completed

Efficacy and Safety of Sotagliflozin Versus Placebo and Empagliflozin in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking a DPP4 Inhibitor Alone or With Metformin

Role: lead

NCT03332771Phase 3Completed

Efficacy and Safety of Sotagliflozin Versus Glimepiride and Placebo in Participants With Type 2 Diabetes Mellitus That Are Taking Metformin Monotherapy

Role: lead

NCT02926950Phase 3Completed

Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus on Background of Metformin

Role: lead

NCT03066830Phase 3Completed

Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus on Background of Sulfonylurea Alone or With Metformin

Role: lead