Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

16.7%

2 terminated/withdrawn out of 12 trials

Success Rate

77.8%

-8.7% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 7 completed trials have results

Key Signals

3 recruiting

Enrollment Performance

Analytics

Phase 1
7(63.6%)
Phase 2
4(36.4%)
11Total
Phase 1(7)
Phase 2(4)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT07217015Phase 2Recruiting

A Study of KT-621 Administered Orally to Participants With Moderate to Severe Atopic Dermatitis

Role: lead

NCT07323654Phase 2Recruiting

A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma

Role: lead

NCT07412288Phase 1Recruiting

First-in-human Study of Orally Administered KT-579 in Healthy Adult Participants

Role: lead

NCT06945458Phase 1Completed

Safety, PK, PD, and Clinical Activity of Orally Administered KT-621 in Adult Patients With Atopic Dermatitis (AD)

Role: lead

NCT06028230Phase 2Terminated

A Phase 2 Study to Evaluate the Efficacy and Safety of SAR444656 Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Role: collaborator

NCT06058156Phase 2Terminated

Phase 2 Study of SAR444656 in Adult Participants With Moderate to Severe Atopic Dermatitis

Role: collaborator

NCT06673667Phase 1Completed

First-in-human Study of Orally Administered KT-621 in Healthy Adult Participants

Role: lead

NCT05225584Phase 1Completed

Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors

Role: lead

NCT05775406Phase 1Completed

Safety and Clinical Activity of KT-253 in Adult Patients with High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors

Role: lead

NCT05233033Phase 1Completed

Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients with Relapsed or Refractory B-cell NHL

Role: lead

NCT04772885Phase 1Completed

A Single and Multiple Ascending Dose Trial of KT-474 in Healthy Adult Volunteers and Patients With Atopic Dermatitis (AD) or Hidradenitis Suppurativa (HS)

Role: lead

NCT04440410Completed

Evaluation of Cutaneous and Circulating Inflammatory Biomarkers in Hidradenitis Suppurativa and Atopic Dermatitis

Role: lead

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