Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

19.0%

4 terminated/withdrawn out of 21 trials

Success Rate

78.9%

-7.6% vs industry average

Late-Stage Pipeline

67%

14 trials in Phase 3/4

Results Transparency

93%

14 of 15 completed trials have results

Key Signals

14 with results

Enrollment Performance

Analytics

Phase 3
9(45.0%)
Phase 4
5(25.0%)
Phase 2
5(25.0%)
Phase 1
1(5.0%)
20Total
Phase 3(9)
Phase 4(5)
Phase 2(5)
Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (21)

Showing 20 of 21 trials
NCT04523727Phase 3Suspended

Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease

Role: lead

NCT04649411Phase 3Withdrawn

Study to Evaluate the Safety and Tolerability of KRX-0502 (Ferric Citrate) in Children With Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease

Role: lead

NCT02661295Phase 4Terminated

A Study of Ferric Citrate to Improve Inflammation and Lipid Levels

Role: collaborator

NCT03079869Phase 4Completed

Transition to Ferric Citrate Among Hemodialysis and Peritoneal Dialysis Patients

Role: collaborator

NCT00130312Phase 4Terminated

Effect of Sulodexide in Overt Diabetic Nephropathy

Role: lead

NCT03236246Phase 4Completed

KRX-0502 (Ferric Citrate) in Subjects With NDD-CKD and IDA (The COMPASS Trial)

Role: lead

NCT00590954Phase 2Completed

Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas

Role: collaborator

NCT03055598Phase 4Active Not Recruiting

Ferric Citrate in ESRD Pilot Project

Role: collaborator

NCT02128074Phase 2Completed

A Pilot Study of KRX-0502 (Ferric Citrate, Administered Without Food, in Treating Iron-deficiency Anemia

Role: lead

NCT02492620Phase 3Completed

Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D

Role: collaborator

NCT00130208Phase 3Completed

Effect of Sulodexide in Early Diabetic Nephropathy

Role: lead

NCT02268994Phase 3Completed

KRX-0502 (Ferric Citrate) for the Treatment of IDA in Adult Subjects With NDD-CKD

Role: lead

NCT01736397Phase 2Completed

Ferric Citrate in Managing Serum Phosphorus and Iron Deficiency in Anemic Chronic Kidney Disease (CKD) Subjects Not on Dialysis

Role: lead

NCT00648167Phase 2Completed

A Safety and Tolerability Study of Zerenex (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD)

Role: lead

NCT00462202Phase 3Terminated

Open Label Tolerability and Safety Study of KRX-101 in Australia, New Zealand, and Hong Kong

Role: lead

NCT01554982Phase 3Completed

A Long-Term Safety Extension Trial of Ferric Citrate in Patients With End-Stage Renal Disease (ESRD) on Dialysis

Role: lead

NCT00431054Phase 1Completed

Perifosine and Docetaxel in Patients With Relapsed Epithelial Ovarian Cancer

Role: collaborator

NCT01191255Phase 3Completed

A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysis

Role: lead

NCT00967993Completed

Trial of a New Formulation of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease

Role: lead

NCT01074125Phase 3Completed

A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease

Role: lead