Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

7.7%

1 terminated/withdrawn out of 13 trials

Success Rate

85.7%

-0.8% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

33%

2 of 6 completed trials have results

Key Signals

4 recruiting2 with results

Enrollment Performance

Analytics

Phase 1
7(53.8%)
Phase 2
6(46.2%)
13Total
Phase 1(7)
Phase 2(6)

Activity Timeline

Global Presence

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Clinical Trials (13)

Showing 13 of 13 trials
NCT03970447Phase 2Recruiting

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Role: collaborator

NCT03994796Phase 2Active Not Recruiting

Genetic Testing in Guiding Treatment for Patients With Brain Metastases

Role: collaborator

NCT07391215Phase 1Recruiting

5G-PEARL: Paxalisib in Malignant Brain Tumours

Role: collaborator

NCT06208657Phase 1Recruiting

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

Role: collaborator

NCT03765983Phase 2Terminated

GDC-0084 in Combination With Trastuzumab for Patients With HER2-Positive Breast Cancer Brain Metastases

Role: collaborator

NCT05183204Phase 2Suspended

Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma

Role: collaborator

NCT05114668Phase 1Completed

Safety, Tolerability, and Pharmacokinetics of EVT801 in Patients With Advanced Solid Tumours

Role: lead

NCT04906096Phase 2Recruiting

Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL

Role: collaborator

NCT03522298Phase 2Completed

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Role: lead

NCT02903771Phase 1Completed

Phase I Study of Cantrixil in Patients With Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer.

Role: lead

NCT05012670Phase 1Completed

Mass Balance Recovery, Metabolite Profile, and Metabolite Identification of [14C]-Paxalisib in Healthy Male Subjects

Role: lead

NCT03696355Phase 1Completed

Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas

Role: collaborator

NCT00022295Phase 1Completed

Phenoxodiol in Treating Patients With Refractory Solid Tumors

Role: lead

All 13 trials loaded