Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

35.7%

5 terminated/withdrawn out of 14 trials

Success Rate

64.3%

-22.2% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

78%

7 of 9 completed trials have results

Key Signals

7 with results

Enrollment Performance

Analytics

Phase 1
7(50.0%)
Phase 2
7(50.0%)
14Total
Phase 1(7)
Phase 2(7)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT05567406Phase 2Withdrawn

Safety and Efficacy of Oral Belumosudil in Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander Male and Female Participants Aged 12 Years and Above With Chronic Graft Versus Host Disease (cGVHD) After At Least 2 Prior Lines of Systemic Therapy

Role: lead

NCT05806567Phase 1Completed

A Study to Assess the Effect of Oral Belumosudil on Inhibition of Various Proteins in the Fed State in Healthy Male Subjects

Role: lead

NCT04242147Phase 1Terminated

A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KD033 (SAR445710) in Subjects With Metastatic or Locally Advanced Solid Tumors

Role: lead

NCT05305989Phase 2Completed

Extended Treatment and Follow-up of Subjects Treated With Belumosudil in Study KD025-208 or Study KD025-213

Role: lead

NCT03640481Phase 2Terminated

Efficacy and Safety of KD025 in Subjects With cGVHD After At Least 2 Prior Lines of Systemic Therapy

Role: lead

NCT03919799Phase 2Terminated

KD025 in Subjects With Diffuse Cutaneous Systemic Sclerosis

Role: lead

NCT02841995Phase 2Completed

A Study to Evaluate the Safety, Tolerability, and Activity of KD025 in Subjects With Chronic Graft Versus Host Disease

Role: lead

NCT05918588Phase 1Completed

A Study to Determine the Effect of Multiple Oral Doses and Regimens of KD025 in Healthy Male and Post-menopausal Female Subjects

Role: lead

NCT05918627Phase 1Completed

A Study to Determine the Effect of Multiple Oral Doses of SLx-2119 in Healthy Male Subjects

Role: lead

NCT05918614Phase 1Completed

A Study to Determine the Effect of 500 mg Oral Dose of KD025 in Healthy Male and Post-menopausal Female Subjects

Role: lead

NCT04680975Phase 2Terminated

Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic Sclerosis

Role: lead

NCT03203642Phase 2Completed

Study of the Efficacy and Safety of Tesevatinib in Subjects With ADPKD

Role: lead

NCT01559363Phase 1Completed

A Safety, Pharmacokinetic & Dose-Escalation Study of KD019 in Subjects With Autosomal Dominant Polycystic Kidney Disease

Role: lead

NCT04166942Phase 1Completed

KD025 Hepatic Impairment Study With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment

Role: lead

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