Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

7.1%

2 terminated/withdrawn out of 28 trials

Success Rate

91.7%

+5.2% vs industry average

Late-Stage Pipeline

11%

3 trials in Phase 3/4

Results Transparency

41%

9 of 22 completed trials have results

Key Signals

9 with results

Enrollment Performance

Analytics

Phase 1
14(53.8%)
Phase 2
9(34.6%)
Phase 3
3(11.5%)
26Total
Phase 1(14)
Phase 2(9)
Phase 3(3)

Activity Timeline

Global Presence

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Clinical Trials (28)

Showing 20 of 28 trials
NCT02494986Phase 2Active Not Recruiting

A Roll-over Study With Rilpivirine for Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants Who Participated in Rilpivirine Pediatric Studies

Role: lead

NCT00980538Phase 3Active Not Recruiting

TMC125-TiDP35-C239 - Continued Access to Etravirine (ETR) in Treatment Experienced HIV-1 Infected Participants

Role: lead

NCT04129554Phase 2Completed

A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection

Role: lead

NCT03982186Phase 2Completed

A Study of Different Combination Regimens Including JNJ-73763989 and/or JNJ-56136379 for the Treatment of Chronic Hepatitis B Virus Infection

Role: lead

NCT04056611Phase 2Terminated

Effects of JNJ-53718678 in Adult and Adolescent Participants Who Had a Hematopoietic Stem Cell Transplantation and Who Are Infected With Respiratory Syncytial Virus (RSV)

Role: lead

NCT03945539Phase 1Completed

A Study to Evaluate the Effect of Itraconazole on JNJ-56136379 in Healthy Adult Participants

Role: lead

NCT02662712Phase 1Completed

A Study of Orally Administered JNJ-56136379 to Evaluate Safety, Tolerability and Pharmacokinetics After Single Ascending Doses and One Multiple Dose Regimen in Healthy Participants (Part I), and After Multiple Dose Regimens in Participants With Chronic Hepatitis B (Part II)

Role: lead

NCT02561936Phase 1Completed

Relative Bioavailability of Three Oral Formulations Candidates of Rilpivirine for Potential Pediatric Use Compared to Oral Tablet

Role: lead

NCT04002752Phase 1Completed

A Study of JNJ-73763989 in Healthy Japanese Adult Participants

Role: lead

NCT02578550Phase 1Completed

A Bioequivalence Study of Darunavir, Emtricitabine, and Tenofovir Alafenamide, in the Presence of Cobicistat in Healthy Participants

Role: lead

NCT00799864Phase 2Completed

A Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Antiviral Activity of Rilpivirine (TMC278) in Human Immunodeficiency Virus Infected Adolescents and Children Aged Greater Than or Equal to 6 Years

Role: lead

NCT03361956Phase 2Completed

An Efficacy, Safety, and Pharmacokinetics Study of JNJ-56136379 in Participants With Chronic Hepatitis B Virus Infection

Role: lead

NCT01281813Phase 3Completed

TMC114IFD3001 - Study Providing Continued Access to Treatment With Darunavir (DRV)/Ritonavir(Rtv) in HIV1 Infected Adults, Adolescents and Children Aged 3 Years or Above and Coming From Previous Company Sponsored Studies With DRV

Role: lead

NCT02387606Phase 2Completed

Study to Evaluate Antiviral Activity, Safety, and Pharmacokinetics of Repeated Doses of Orally Administered JNJ 53718678 Against Respiratory Syncytial Virus Infection.

Role: lead

NCT02431247Phase 3Completed

A Study to Evaluate Efficacy and Safety of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed Dose Combination (FDC) Versus a Regimen Consisting of Darunavir/Cobicistat FDC With Emtricitabine/Tenofovir Disoproxil Fumarate FDC in Treatment-naive HIV Type 1 Infected Subjects

Role: lead

NCT04221412Unknown

Pre-Approval Access to JNJ-53718678 for the Treatment of Respiratory Syncytial Virus (RSV) Infection in (a) Immunocompromised Adult and Pediatric Participants

Role: lead

NCT04208399Phase 1Completed

A Study to Evaluate the Effect of Hepatic Impairment on JNJ-56136379

Role: lead

NCT03463369Phase 1Completed

A First-In-Human Study to Evaluate Safety, Tolerability, Reactogenicity, and Immunogenicity of JNJ-64300535, a DNA Vaccine, Administered by Electroporation-Mediated Intramuscular Injection, in Participants With Chronic Hepatitis B Who Are on Stable Nucleos(t)Ide Therapy and Virologically Suppressed

Role: lead

NCT03847376Unknown

Pre-Approval Access to Rilpivirine Long Acting (RPV LA) Injectable Suspension for the Treatment of a Participant With Human Immunodeficiency Virus (HIV)-1 Infection

Role: lead

NCT04208386Phase 1Completed

A Study to Evaluate the Effect of Hepatic Impairment on JNJ-73763989

Role: lead