Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

8.3%

1 terminated/withdrawn out of 12 trials

Success Rate

66.7%

-19.8% vs industry average

Late-Stage Pipeline

8%

1 trials in Phase 3/4

Results Transparency

100%

2 of 2 completed trials have results

Key Signals

5 recruiting2 with results

Enrollment Performance

Analytics

Early Phase 1
10(83.3%)
Phase 2
1(8.3%)
Phase 3
1(8.3%)
12Total
Early Phase 1(10)
Phase 2(1)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT06388733Phase 3Recruiting

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Role: lead

NCT05940493Phase 2Recruiting

Abemaciclib in Newly Diagnosed Meningioma Patients

Role: collaborator

NCT05076513Early Phase 1Active Not Recruiting

Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma

Role: collaborator

NCT05182905Early Phase 1Active Not Recruiting

AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients

Role: collaborator

NCT04391595Early Phase 1Completed

LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients

Role: collaborator

NCT02933736Early Phase 1Active Not Recruiting

Ribociclib (LEE011) in Preoperative Glioma and Meningioma Patients

Role: collaborator

NCT06072586Early Phase 1Recruiting

A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions

Role: collaborator

NCT04424966Early Phase 1Terminated

Infigratinib in Recurrent High-Grade Glioma Patients

Role: collaborator

NCT03834740Early Phase 1Completed

A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection

Role: collaborator

NCT04559685Early Phase 1Recruiting

Study of Sonodynamic Therapy in Participants with Recurrent High-Grade Glioma

Role: collaborator

NCT04614909Early Phase 1Active Not Recruiting

Study of Pamiparib in Newly Diagnosed and rGBM

Role: collaborator

NCT05773326Early Phase 1Recruiting

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

Role: collaborator

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