Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

9.5%

2 terminated/withdrawn out of 21 trials

Success Rate

89.5%

+3.0% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

24%

4 of 17 completed trials have results

Key Signals

2 recruiting4 with results

Enrollment Performance

Analytics

Phase 1
12(57.1%)
Early Phase 1
7(33.3%)
N/A
2(9.5%)
21Total
Phase 1(12)
Early Phase 1(7)
N/A(2)

Activity Timeline

Global Presence

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Clinical Trials (21)

Showing 20 of 21 trials
NCT07348276Early Phase 1Recruiting

First-in-Human Study for the Safety and Evaluation of Two 4R Tau Ligands as Potential PET Radioligands for Imaging Tau Protein in the Brain

Role: lead

NCT07348250Early Phase 1Recruiting

Open-label Study to Evaluate Brain α-Synuclein Deposition Using PET and [18F]MK-0947 in Parkinson's Disease

Role: lead

NCT05725005Phase 1Completed

PET Study of Repeated ASN51 in Healthy Volunteers

Role: collaborator

NCT06456723Phase 1Completed

Evaluation of [18F]Fluoroethyl Triazole Labelled [Tyr3]-Octreotate Analogues for the Imaging of Neuroendocrine Tumours.

Role: collaborator

NCT05164536Phase 1Completed

Plasma P-tau2017 and Quantitative Amyloid PET Imaging

Role: lead

NCT05274568Phase 1Completed

Proof of Mechanism Study to Evaluate Binding of Alfa-synuclein

Role: lead

NCT05005819Phase 1Completed

Evaluation of [18F]APN-1607 as a PET Biomarker

Role: lead

NCT06445465Early Phase 1Completed

Study to Evaluate a Potential PET Radioligand for Imaging Alpha-synuclein Deposits in the Brain

Role: lead

NCT04116164Early Phase 1Terminated

Safety and Targeting of Anti-hk2 Antibody in mCRPC

Role: collaborator

NCT05063357Phase 1Withdrawn

131I-omburtamab Delivered by Convection-Enhanced Delivery in Patients With Diffuse Intrinsic Pontine Glioma

Role: collaborator

NCT05009199Phase 1Completed

Occupancy of Adenosine A2A Receptors Using the PET Radiotracer [18F]MNI-444

Role: lead

NCT04394845Phase 1Completed

A Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants

Role: collaborator

NCT04851392Not ApplicableCompleted

Do Adolescents and Adults Differ in Their Acute Response to Cannabis?

Role: collaborator

NCT03662750Not ApplicableCompleted

TSPO PET as a Measure of Post-stroke Brain Inflammation: a Natural History Cohort

Role: collaborator

NCT03071224Early Phase 1Completed

Phase 1 Evaluation of [18F]MK-6240 PET as an Imaging Marker for Tau Protein

Role: lead

NCT03587649Phase 1Completed

Evaluation of [18F]MNI-1126 as an Imaging Marker for Synaptic Density Loss

Role: lead

NCT03545789Phase 1Completed

Phase 1 Test-retest Evaluation of [18F]MNI-958 PET

Role: lead

NCT03719482Phase 1Completed

Assessment of the Biodistribution and Safety of [18F]MNI-1054

Role: lead

NCT03695926Early Phase 1Completed

Assessment of [18F]MNI-1054 as a Marker for LSD1

Role: lead

NCT03686501Early Phase 1Completed

D1 Receptor Occupancy (RO) Following a Single Dose of PF-06412562

Role: lead