Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

18.2%

4 terminated/withdrawn out of 22 trials

Success Rate

66.7%

-19.8% vs industry average

Late-Stage Pipeline

27%

6 trials in Phase 3/4

Results Transparency

13%

1 of 8 completed trials have results

Key Signals

2 recruiting1 with results

Enrollment Performance

Analytics

Phase 2
7(41.2%)
Phase 3
6(35.3%)
N/A
4(23.5%)
17Total
Phase 2(7)
Phase 3(6)
N/A(4)

Activity Timeline

Global Presence

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Clinical Trials (22)

Showing 20 of 22 trials
NCT05889221Not ApplicableActive Not Recruiting

Multicenter Phase 2 Study of Subcutaneous Isatuximab Plus Bortezomib, Lenalidomide and Dexamethasone in the Treatment of Newly Diagnosed Transplant Ineligible Multiple Myeloma

Role: collaborator

NCT06062537Active Not Recruiting

Analysis of Effectiveness and Safety of Teclistamab in Relapsed and Refractory Multiple Myeloma Patients

Role: lead

NCT05208086Active Not Recruiting

Diagnostic Performance of Spot Urine Sample for the Monoclonal Components Detection in Patients With Multiple Myeloma

Role: lead

NCT06918002Phase 3Recruiting

Elranatamab/Lenalidomide Consolidation and/or Elranatamab Maintenance Versus Standard of Care After D-VRd Induction in Transplant-eligible NDMM Patients

Role: lead

NCT04751877Phase 3Active Not Recruiting

Multicenter Open Label Phase 3 Study of Isatuximab Plus Lenalidomide and Dexamethasone With/Without Bortezomib in the Treatment of Newly Diagnosed Non Frail Transplant Ineligible Multiple Myeloma Elderly Patients (≥ 65; < 80 Years).

Role: collaborator

NCT02244125Phase 2Completed

A Multicenter Open Label Phase II Study of Pomalidomide and Cyclophosphamide and Dexamethasone in Relapse/Refractory Multiple Myeloma Patients Who Were First Treated Within the IFM/DFCI 2009 Trial (PCD)

Role: collaborator

NCT04111809Terminated

Study of 4 Bone Turnover Markers in Patients With Multiple Myeloma Treated With Intravenous Bisphosphonate in Routine Care

Role: collaborator

NCT02541383Phase 3Completed

A Study to Evaluate Daratumumab in Transplant Eligible Participants With Previously Untreated Multiple Myeloma

Role: lead

NCT03683277Phase 2Terminated

IPD in RRMM Characterized with Genomic Abnormalities of Adverse Prognostic

Role: lead

NCT04934475Phase 3Active Not Recruiting

MInimal Residual Disease Adapted Strategy

Role: lead

NCT05066607Phase 2Recruiting

Isatuximab Plus Pomalidomide and Dexamethasone Association for Patients With AL Amyloidosis Not in VGPR or Better After Any Previous Therapy

Role: lead

NCT04144387Not ApplicableActive Not Recruiting

Evaluation of the Impact of the Update SMM Criteria on the Natural History of SMM to Establish New Recommendations.

Role: lead

NCT04805203Not ApplicableTerminated

Analysis of the Immune Parameters of COVID-19 Infection in Patients With Multiple Myeloma

Role: lead

NCT04287855Phase 2Active Not Recruiting

Multicenter Open Label Phase 2 Study of Isatuximab Plus Pomalidomide and Dexamethasone With Carfilzomib in Relapsed or Refractory Multiple Myeloma

Role: collaborator

NCT01079429Terminated

Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM.

Role: collaborator

NCT00907452Not ApplicableCompleted

Pharmacogenomic Study in Myeloma Patients Treated With Melphalan-prednisone-thalidomide or Lenalidomide-dexamethasone

Role: lead

NCT02626481Phase 2Completed

Study of Daratumumab in Combination With Dexamethasone in Resistant or Refractory Multiple Myeloma

Role: collaborator

NCT01045681Phase 2Completed

Study of Bendamustine, Velcade and Dexamethasone in the Treatment of Elderly Patients With Multiple Myeloma

Role: lead

NCT00430365Phase 3Completed

Maintenance Therapy Using Lenalidomide in Myeloma

Role: collaborator

NCT00642395Phase 2Completed

Velcade®-Melphalan Association in Autologous Stem-Cell Transplantation (ASCT)

Role: collaborator