Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

12.9%

12 terminated/withdrawn out of 93 trials

Success Rate

80.3%

-6.2% vs industry average

Late-Stage Pipeline

5%

5 trials in Phase 3/4

Results Transparency

29%

14 of 49 completed trials have results

Key Signals

12 recruiting14 with results7 terminated5 withdrawn

Enrollment Performance

Analytics

N/A
66(76.7%)
Phase 1
8(9.3%)
Phase 2
5(5.8%)
Phase 3
4(4.7%)
Early Phase 1
2(2.3%)
Phase 4
1(1.2%)
86Total
N/A(66)
Phase 1(8)
Phase 2(5)
Phase 3(4)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (93)

Showing 20 of 93 trials
NCT06584383Not ApplicableActive Not Recruiting

A Prospective, Randomized, Controlled Trial to Test Safety and Effectiveness of Unilateral Exablate MR-guided Focused Ultrasound Subthalamotomy in Patients With Early-Stage Parkinson's Disease

Role: lead

NCT05089786Not ApplicableWithdrawn

Echo-Focusing in Patients With Treatment-Resistant Neurologic and Psychiatric Indications (EF001)

Role: lead

NCT05615623Phase 1Active Not Recruiting

Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG

Role: lead

NCT02246374Not ApplicableCompleted

ExAblate Transcranial MRgFUS of the Subthalamic Nucleus for Treatment of Parkinson's Disease

Role: lead

NCT05630209Phase 1Active Not Recruiting

Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG)

Role: lead

NCT05317858Phase 3Recruiting

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

Role: lead

NCT04998864Completed

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients

Role: lead

NCT06974916Not ApplicableRecruiting

EMBRACE Tremor BiFUS

Role: lead

NCT03454425Not ApplicableCompleted

A Study to Evaluate the Safety and Efficacy of ExAblate Subthalomotomy for the Treatment of Parkinson's Disease Motor Features

Role: lead

NCT03321487Not ApplicableCompleted

Blood-Brain Barrier Opening Using MR-Guided Focused Ultrasound in Patients With Amyotrophic Lateral Sclerosis

Role: lead

NCT03714243Not ApplicableCompleted

Blood Brain Barrier Disruption (BBBD) Using MRgFUS in the Treatment of Her2-positive Breast Cancer Brain Metastases

Role: lead

NCT03964272Not ApplicableCompleted

A Feasibility Study on the Safety and Preliminary Efficacy of Bilateral Subthalamotomy Using MRgFUS for Treatment of PD

Role: lead

NCT03608553Not ApplicableCompleted

A Study to Evaluate Temporary Blood Brain Barrier Disruption in Patients With Parkinson's Disease Dementia

Role: lead

NCT05539196Recruiting

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

Role: lead

NCT04417088Phase 1Completed

Exablate Blood-Brain Barrier Disruption for the Treatment of rGBM in Subjects Undergoing Carboplatin Monotherapy

Role: lead

NCT03551249Not ApplicableCompleted

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption

Role: lead

NCT04197921Not ApplicableRecruiting

Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Use Disorders (SUDs)

Role: lead

NCT04370665Not ApplicableCompleted

Blood-Brain-Barrier Disruption With Cerezyme in Patient's With Parkinson's Disease

Role: lead

NCT04649554Not ApplicableTerminated

Study of MRgFUS Exablate Treatment Following the Neuropathic Pain

Role: lead

NCT03465761Not ApplicableCompleted

Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor

Role: lead