Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 90/100

Failure Rate

32.1%

9 terminated/withdrawn out of 28 trials

Success Rate

65.4%

-21.1% vs industry average

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

6%

1 of 17 completed trials have results

Key Signals

1 with results6 terminated

Enrollment Performance

Analytics

Phase 1
15(53.6%)
Phase 2
11(39.3%)
Phase 3
1(3.6%)
N/A
1(3.6%)
28Total
Phase 1(15)
Phase 2(11)
Phase 3(1)
N/A(1)

Activity Timeline

Global Presence

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Clinical Trials (28)

Showing 20 of 28 trials
NCT03719326Phase 1Completed

A Study to Evaluate Safety/Tolerability of Immunotherapy Combinations in Participants With Triple-Negative Breast Cancer or Gynecologic Malignancies

Role: collaborator

NCT03961698Phase 2Unknown

Evaluation of IPI-549 Combined With Front-line Treatments in Pts. With Triple-Negative Breast Cancer or Renal Cell Carcinoma

Role: lead

NCT03980041Phase 2Completed

Study to Evaluate the Efficacy/Safety of IPI-549 in Combination With Nivolumab in Patients With Advanced Urothelial Carcinoma (MARIO-275)

Role: lead

NCT02637531Phase 1Unknown

A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549

Role: lead

NCT01228435Phase 2Terminated

IPI-504 in NSCLC Patients With ALK Translocations

Role: collaborator

NCT01383538Phase 1Completed

FOLFIRINOX Plus IPI-926 for Advanced Pancreatic Adenocarcinoma

Role: collaborator

NCT01130142Phase 1Completed

A Study Evaluating IPI-926 in Combination With Gemcitabine in Patients With Metastatic Pancreatic Cancer

Role: lead

NCT02598570Phase 1Completed

Study Evaluating Duvelisib in Japanese Subjects With Relapsed or Refractory Lymphoma

Role: collaborator

NCT02640833Phase 1Withdrawn

A Study of Duvelisib and Venetoclax in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Indolent or Aggressive Non-Hodgkin Lymphoma, Who Have Not Previously Received a Bcl-2 or PI3K Inhibitor

Role: collaborator

NCT01871675Phase 1Completed

Study of IPI-145 in Combination With Rituximab or Bendamustine/Rituximab in Hematologic Malignancies

Role: collaborator

NCT01193491Phase 1Terminated

Dose Escalation of IPI-493 in Hematologic Malignancies

Role: lead

NCT00724425Phase 1Terminated

A Phase 1 Dose Escalation Study of IPI-493

Role: lead

NCT00969917Phase 2Withdrawn

Study Evaluating the Efficacy and Safety of IPI 504 in Patients With Advanced Dedifferentiated Liposarcoma

Role: lead

NCT01427946Phase 1Completed

Phase 1b/2 Study of Retaspimycin HCl (IPI-504) in Combination With Everolimus in KRAS Mutant Non-small Cell Lung Cancer

Role: lead

NCT01362400Phase 2Completed

A Double-blind Study Evaluating IPI-504 and Docetaxel in Patients With Non-Small Cell Lung Cancer

Role: lead

NCT02028039Phase 2Withdrawn

IPI-145 in Relapsed Refractory Acute Lymphoblastic Leukemia (ALL)

Role: collaborator

NCT01310816Phase 2Completed

A Safety and Efficacy Study of Patients With Metastatic or Locally Advanced (Unresectable) Chondrosarcoma

Role: lead

NCT00688766Phase 3Terminated

Study Evaluating IPI-504 in Patients With Gastrointestinal Stromal Tumors (GIST) Following Failure of at Least Imatinib and Sunitinib

Role: lead

NCT00817362Phase 2Terminated

Efficacy and Safety of IPI-504 With Trastuzumab Pretreated, Locally Advanced or Metastatic HER2 Positive Breast Cancer

Role: lead

NCT00564928Phase 2Completed

A Phase 2 Study to Investigate the Clinical Activity of IPI-504 in Patients With Hormone-resistant Prostate Cancer

Role: lead