Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

50.0%

5 terminated/withdrawn out of 10 trials

Success Rate

50.0%

-36.5% vs industry average

Late-Stage Pipeline

10%

1 trials in Phase 3/4

Results Transparency

80%

4 of 5 completed trials have results

Key Signals

4 with results

Enrollment Performance

Analytics

Phase 1
7(70.0%)
Phase 2
2(20.0%)
Phase 3
1(10.0%)
10Total
Phase 1(7)
Phase 2(2)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (10)

Showing 10 of 10 trials
NCT02406781Phase 2Completed

Combination of MK3475 and Metronomic Cyclophosphamide in Patients With Advanced Sarcomas : Multicentre Phase II Trial

Role: collaborator

NCT04222985Phase 1Terminated

Safety and Efficacy of 4 Investigational HSV 2 Vaccines in Adults With Recurrent Genital Herpes Caused by HSV 2

Role: collaborator

NCT02501473Phase 1Terminated

Study of Intratumoral G100 With Or Without Pembrolizumab or Rituximab In Participants With Follicular Non-Hodgkin's Lymphoma (MK-3475-174/IMDZ-G142)

Role: lead

NCT02609984Phase 2Terminated

Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002)

Role: lead

NCT02387125Phase 1Terminated

Phase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1

Role: lead

NCT03520959Phase 3Terminated

A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)

Role: lead

NCT02122861Phase 1Completed

Phase 1 Study of Intradermal LV305 in Patients With Locally Advanced, Relapsed or Metastatic Cancer Expressing NY-ESO-1

Role: lead

NCT02035657Phase 1Completed

A Proof-of-Concept Trial of GLA-SE in Patients With Merkel Cell Carcinoma

Role: lead

NCT02015416Phase 1Completed

A Phase 1 Trial of NY-ESO-1 With GLA-SE in Patients With Unresectable or Metastatic Cancer

Role: lead

NCT01397604Phase 1Completed

The Effects of GLA on Human Volunteers

Role: collaborator

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