Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

13.3%

2 terminated/withdrawn out of 15 trials

Success Rate

84.6%

-1.9% vs industry average

Late-Stage Pipeline

7%

1 trials in Phase 3/4

Results Transparency

100%

11 of 11 completed trials have results

Key Signals

1 recruiting11 with results

Enrollment Performance

Analytics

Phase 2
7(46.7%)
Phase 1
7(46.7%)
Phase 3
1(6.7%)
15Total
Phase 2(7)
Phase 1(7)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (15)

Showing 15 of 15 trials
NCT04196283Phase 1Completed

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Role: collaborator

NCT03445533Phase 3Terminated

A Study of Tilsotolimod in Combo With Ipilimumab vs Ipilimumab Alone in Subjects With Anti-PD-1 Refractory Melanoma

Role: lead

NCT02644967Phase 2Completed

A Phase 2 Study to Assess the Safety and Efficacy of IMO-2125 With 8 mg Ipilimumab in Patients With Metastatic Melanoma

Role: lead

NCT01899729Phase 2Completed

A 12-week Dose-Ranging Trial in Patients With Moderate to Severe Plaque Psoriasis

Role: lead

NCT03865082Phase 2Active Not Recruiting

Study of Tilsotolimod in Combination With Nivolumab and Ipilimumab for the Treatment of Solid Tumors (ILLUMINATE-206)

Role: lead

NCT04126876Phase 2Recruiting

A Randomized Controlled Phase II Trial With Intradermal IMO-2125 in Pathological Tumor Stage (p) T3-4 cN0M0 Melanoma

Role: collaborator

NCT03052205Phase 1Completed

A Study of Intratumoral IMO-2125 in Patients With Refractory Solid Tumors

Role: lead

NCT02612857Phase 2Completed

Trial of IMO-8400 in Adult Patients With Dermatomyositis

Role: lead

NCT02092909Phase 1Terminated

Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia

Role: lead

NCT00990938Phase 1Completed

Study of Combination Treatment With IMO-2125 and Ribavirin in Naïve Hepatitis C-infected, Genotype 1 Patients

Role: lead

NCT00728936Phase 1Completed

Placebo-controlled, Dose-escalation Study of the Safety of IMO-2125 (Immunomodulatory Oligonucleotide) in Hepatitis C-infected Patients

Role: lead

NCT00729053Phase 2Completed

Study of IMO-2055 in Metastatic or Locally Recurrent Clear Cell Renal Carcinoma

Role: lead

NCT01622348Phase 2Completed

Trial of IMO-3100 in Patients With Moderate to Severe Plaque Psoriasis

Role: lead

NCT02363439Phase 1Completed

Extension Study of IMO-8400 in Patients With Waldenström's Macroglobulinemia Who Completed Study 8400-401

Role: lead

NCT02252146Phase 1Completed

Dose Escalation Study in Patients With Relapsed or Refractory DLBCL and MyD88 L265P Mutation

Role: lead

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