Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

16.7%

2 terminated/withdrawn out of 12 trials

Success Rate

75.0%

-11.5% vs industry average

Late-Stage Pipeline

8%

1 trials in Phase 3/4

Results Transparency

50%

3 of 6 completed trials have results

Key Signals

3 with results

Enrollment Performance

Analytics

Phase 1
7(58.3%)
Phase 2
4(33.3%)
Phase 3
1(8.3%)
12Total
Phase 1(7)
Phase 2(4)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT05141357Phase 2Terminated

A Study of HBI-8000 (Tucidinostat) With Pembrolizumab in Non-Small Cell Lung Cancer

Role: lead

NCT04680026Phase 2Active Not Recruiting

A Study of IV HBI-3000 for the Conversion Recent Onset Atrial Fibrillation (AF)

Role: lead

NCT04674683Phase 3Active Not Recruiting

Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced Melanoma

Role: lead

NCT05485974Phase 1Active Not Recruiting

A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation

Role: lead

NCT05163028Phase 1Active Not Recruiting

A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations

Role: lead

NCT02955589Phase 2Completed

Efficacy and Safety of Oral HBI-8000 in Patients With Relapsed or Refractory Adult T Cell Lymphoma (ATL)

Role: lead

NCT02953652Phase 2Completed

Efficacy and Safety of Oral HBI-8000 in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

Role: lead

NCT02718066Phase 1Completed

Study of HBI-8000 With Nivolumab in Melanoma, Renal Cell Carcinoma and Non-Small Cell Lung Cancer

Role: lead

NCT02569489Phase 1Withdrawn

Dose Escalation Study of HBI-8000 in Combination With Paclitaxel and Trastuzumab in Women With Advanced or Metastatic HER2+ Breast Cancer

Role: lead

NCT04650542Phase 1Completed

Drug-Drug Interaction Study of HBI-3000 and Paroxetine in Healthy Adult Male and Female Subjects

Role: lead

NCT03397641Phase 1Completed

A Phase 1 Study of HBI-3000

Role: lead

NCT02697552Phase 1Completed

Safety Study of HBI-8000 in Japanese Patients With Non Hodgkin's Lymphoma

Role: lead

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