Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 15/100

Failure Rate

10.7%

3 terminated/withdrawn out of 28 trials

Success Rate

88.0%

+1.5% vs industry average

Late-Stage Pipeline

46%

13 trials in Phase 3/4

Results Transparency

59%

13 of 22 completed trials have results

Key Signals

13 with results

Enrollment Performance

Analytics

Phase 2

13(48.1%)

Phase 4

7(25.9%)

Phase 3

6(22.2%)

Phase 1

1(3.7%)

27Total

Phase 2(13)

Phase 4(7)

Phase 3(6)

Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (28)

Showing 20 of 28 trials

NCT02689258Phase 2Completed

Evaluation of the Efficacy and Safety of HTX-011 for Postoperative Analgesia Following Abdominoplasty Surgery

Role: lead

NCT00343460Phase 3Completed

APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer

Role: lead

NCT03295721Phase 3Completed

Bunionectomy Study for Postoperative Analgesia (EPOCH 1)

Role: lead

NCT02504580Phase 2Completed

Pilot Herniorrhaphy Study for Postoperative Analgesia

Role: lead

NCT04470622Phase 2Terminated

Aprepitant Injectable Emulsion in Patients With COVID-19 (GUARDS-1)

Role: lead

NCT03237481Phase 3Completed

Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)

Role: lead

NCT02106494Phase 3Completed

A Prospective, Multicenter, Study of APF530 (Granisetron) SC for Prevention of CINV in Patients Receiving HEC

Role: lead

NCT03015532Phase 2Completed

Total Knee Arthroplasty Infiltration Study for Postoperative Analgesia

Role: lead

NCT03718039Phase 2Completed

Phase 2 Bunionectomy HTX-011 Administration Study

Role: lead

NCT03974932Phase 3Completed

Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen

Role: lead

NCT03011333Phase 2Completed

Phase 2B Upper Extremity Nerve Block Study

Role: lead

NCT03695367Phase 2Completed

Phase 2 Herniorrhaphy Study for Opioid Elimination

Role: lead

NCT02762929Phase 2Completed

Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy

Role: lead

NCT01416259Completed

A Phase I Study of the Effects of APF530 Exposure, Granisetron and Moxifloxacin

Role: lead

NCT06109428Phase 4Completed

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE

Role: lead

NCT06109415Phase 4Completed

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.

Role: lead

NCT05109312Phase 4Unknown

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.

Role: lead

NCT05434663Phase 4Unknown

Safety Study of Repeat Doses of SUSTOL in Adults

Role: lead

NCT04911062Phase 2Completed

HTX-011 in Spinal Surgery

Role: lead

NCT03922048Phase 2Withdrawn

Pediatric Postoperative Analgesia Herniorrhaphy Study

Role: lead