Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

4.5%

1 terminated/withdrawn out of 22 trials

Success Rate

91.7%

+5.2% vs industry average

Late-Stage Pipeline

9%

2 trials in Phase 3/4

Results Transparency

9%

1 of 11 completed trials have results

Key Signals

4 recruiting1 with results

Enrollment Performance

Analytics

Phase 1
9(45.0%)
Phase 2
9(45.0%)
Phase 3
2(10.0%)
20Total
Phase 1(9)
Phase 2(9)
Phase 3(2)

Activity Timeline

Global Presence

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Clinical Trials (22)

Showing 20 of 22 trials
NCT01710176Phase 3Completed

Localized High-Risk Soft Tissue Sarcomas Of The Extremities And Trunk Wall In Adults: An Integrating Approach Comprising Standard Vs Histotype-Tailored Neoadjuvant Chemotherapy

Role: collaborator

NCT05146440Phase 1Recruiting

Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor

Role: lead

NCT05809830Phase 1Active Not Recruiting

Phase I/II of LB-100 Plus Doxorubicin vs. Doxorubicin Alone in First Line of Advanced Soft Tissue Sarcomas

Role: lead

NCT04181970Recruiting

Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK

Role: lead

NCT03277924Phase 1Completed

Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas

Role: lead

NCT04595994Phase 1Recruiting

Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma and Osteosarcoma

Role: lead

NCT03242382Phase 2Unknown

Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression.

Role: lead

NCT02275286Phase 1Recruiting

Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients

Role: lead

NCT02066285Phase 2Completed

Trial of Pazopanib in Patients With Solitary Fibrous Tumor and Extraskeletal Myxoid Chondrosarcoma

Role: lead

NCT03985722Phase 1Unknown

Olaratumab Plus Trabectedin in Advanced Soft-tissue Sarcoma Patients Soft-tissue Sarcoma Patients

Role: lead

NCT05131386Phase 2Unknown

Multicohort Trial of Trabectedin and Low-dose Radiation Therapy in Advanced/Metastatic Sarcomas

Role: lead

NCT02638766Phase 2Completed

Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST

Role: lead

NCT04138381Phase 1Unknown

Selinexor as Single Agent and With Imatinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (SeliGIST)

Role: lead

NCT03275818Phase 2Completed

Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma

Role: lead

NCT04383288Completed

ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

Role: lead

NCT01692496Phase 2Completed

Activity and Tolerability of Pazopanib in Advanced and/or Metastatic Liposarcoma. A Phase II Clinical Trial

Role: lead

NCT01696669Phase 2Completed

Study of Intensive Chemotherapy, Surgery and Radiotherapy to Treat Ewing's Sarcoma in Children and Young Adults

Role: lead

NCT00103168Phase 3Completed

Imatinib Mesylate or Observation Only in Treating Patients Who Have Undergone Surgery for Localized Gastrointestinal Stromal Tumor

Role: collaborator

NCT01684449Phase 1Completed

Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma

Role: lead

NCT01104298Phase 2Terminated

Doxorubicin vs. Trabectedin Plus Doxorubicin in Non Operable and/or Metastatic STS

Role: lead