Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

14.7%

5 terminated/withdrawn out of 34 trials

Success Rate

79.2%

-7.3% vs industry average

Late-Stage Pipeline

50%

17 trials in Phase 3/4

Results Transparency

5%

1 of 19 completed trials have results

Key Signals

1 recruiting1 with results

Enrollment Performance

Analytics

Phase 3
17(51.5%)
Phase 2
14(42.4%)
Phase 1
2(6.1%)
33Total
Phase 3(17)
Phase 2(14)
Phase 1(2)

Activity Timeline

Global Presence

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Clinical Trials (34)

Showing 20 of 34 trials
NCT07529873Phase 2Not Yet Recruiting

Phase II Study of Ficerafusp Alfa in Combination With Nivolumab in Patients With Platinum-refractory Head and Neck Squamous Cell Carcinoma

Role: lead

NCT07264075Phase 3Not Yet Recruiting

Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus Pembrolizumab for the Treatment of SCCHN

Role: lead

NCT03070366Phase 2Active Not Recruiting

Stereotactic Radiotherapy Combined With Chemotherapy or Not for Treatment of Oligometastases in HNSCC

Role: lead

NCT06959108Phase 2Not Yet Recruiting

Clinical Trial Comparing Induction Treatment With EGFR-ADC MRG003 Alone or in Combination With the Anti PD1 Pucotenlimab, Followed by Radiochemotherapy in Locally Advanced Squamous Cell Cancers of the Head and Neck

Role: lead

NCT03340896Phase 3Active Not Recruiting

Trial of Laryngeal Preservation Comparing Induced CT Followed by RT vs CT Concomitant to RT

Role: lead

NCT04356170Phase 2Completed

Trial Evaluating Adapted Chemotherapy in Patients With Squamous Carcinoma

Role: lead

NCT05930938Phase 3Terminated

Study Comparing RT With Cetuximab + Xevinapant to RT With Cetuximab-placebo in Patients With Head and Neck Cancer

Role: lead

NCT05930951Phase 1Terminated

Study of OBT076 Associated or Not in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma of the Head and Neck

Role: lead

NCT02999087Phase 3Active Not Recruiting

Randomized Trial of Avelumab-cetuximab-radiotherapy Versus SOCs in LA SCCHN (REACH)

Role: lead

NCT03576417Phase 3Active Not Recruiting

A Trial Evaluating the Addition of Nivolumab to Cisplatin-RT for Treatment of Cancers of the Head and Neck

Role: lead

NCT02998385Phase 3Active Not Recruiting

Chemo-radiotherapy Versus Radiotherapy in the Treatment of Salivary Glands and Nasal Tumors (IMRT or Protontherapy)

Role: lead

NCT03726775Phase 2Active Not Recruiting

Trial Evaluating the Tolerance and Safety of Durvalumab - RT Combination for Treatment in SCCHN

Role: lead

NCT06640725Phase 2Recruiting

Study of TPEx Followed by a Maintenance With Avelumab and Cetuximab in First Line Recurrent or Metastatic Squamous Cell Carcinoma of the H&N

Role: lead

NCT01864850Phase 3Completed

Non Inferiority Trial of Standard RT Versus Hypofractionated Split Course in Elderly Vulnerable Patients With HNSCC

Role: lead

NCT02707588Phase 2Completed

Tolerance and Efficacy of Pembrolizumab or Cetuximab Combined With RT in Patients With Locally Advanced HNSCC

Role: lead

NCT02268695Phase 2Completed

Platinum-Cetuximab Combined With Docetaxel or With 5FU in Patients With Recurrent/Metastatic HNSCC

Role: lead

NCT01864772Phase 2Completed

Phase II Trial of Carboplatin, 5-FU and Cetuximab in Elderly Fit (no Frailty) Patients With Recurrent/Metastatic HNSCC

Role: lead

NCT03330249Phase 2Completed

Comparison of Two Concomitant Administration of RT With Cisplatin in Standard Infusion or Fractional Infusion

Role: lead

NCT00609284Phase 3Completed

Randomized Trial of Concomitant Chemotherapy in Patients With Locally Advanced HNSCC Treated by Radiotherapy-erbitux

Role: lead

NCT00158678Phase 3Completed

IMRT Plus Cisplatin Versus Conventional Radiotherapy Plus Cisplatin in Stage III-IV HNSCC

Role: lead