Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

25.0%

4 terminated/withdrawn out of 16 trials

Success Rate

71.4%

-15.1% vs industry average

Late-Stage Pipeline

6%

1 trials in Phase 3/4

Results Transparency

80%

8 of 10 completed trials have results

Key Signals

8 with results

Enrollment Performance

Analytics

Phase 2
10(66.7%)
Phase 1
4(26.7%)
Phase 3
1(6.7%)
15Total
Phase 2(10)
Phase 1(4)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (16)

Showing 16 of 16 trials
NCT02346747Phase 2Active Not Recruiting

A Trial of Vigil for Participants With Ovarian Cancer

Role: lead

NCT01309230Phase 2Completed

A Trial of FANG™ Vaccine for Participants With Ovarian Cancer

Role: lead

NCT03842865Unknown

Expanded Access of Vigil in Solid Tumors

Role: lead

NCT02736565Phase 1Completed

Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's Sarcoma

Role: lead

NCT03495921Phase 3Terminated

A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and Temozolomide

Role: lead

NCT03073525Phase 2Completed

A Trial of Atezolizumab and Vigil in Patients With Advanced Gynecological Cancers

Role: lead

NCT02511132Phase 2Completed

A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcoma

Role: lead

NCT01061840Phase 1Completed

Trial of Bi-shRNA-furin and GMCSF Augmented Autologous Tumor Cell Vaccine for Advanced Cancer

Role: lead

NCT01505166Phase 2Terminated

Randomized Phase II Adjuvant Chemotherapy ± FANG™ in Colorectal Carcinoma With Liver Metastases

Role: lead

NCT01551745Phase 2Completed

Salvage Ovarian FANG™ Vaccine + Bevacizumab

Role: lead

NCT02725489Phase 2Completed

Pilot Study of Durvalumab and Vigil in Advanced Women's Cancers

Role: collaborator

NCT01867086Phase 2Completed

Salvage Ovarian FANG™ Vaccine + Carboplatinum

Role: lead

NCT01453361Phase 2Terminated

Phase II FANG™ in Advanced Melanoma

Role: lead

NCT01505153Phase 1Completed

Phase I Intratumoral Pbi-shRNA STMN1 LP in Advanced and/or Metastatic Cancer

Role: lead

NCT02574533Phase 1Completed

Pilot Study of Vigil™ + Pembrolizumab for Advanced Melanoma

Role: lead

NCT02639234Phase 2Withdrawn

Vigil™ + Nivolumab in Advanced Non-Small Cell Lung Cancer

Role: lead

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