Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 20/100

Failure Rate

12.7%

7 terminated/withdrawn out of 55 trials

Success Rate

61.1%

-25.4% vs industry average

Late-Stage Pipeline

55%

30 trials in Phase 3/4

Results Transparency

127%

14 of 11 completed trials have results

Key Signals

18 recruiting14 with results

Enrollment Performance

Analytics

Phase 3
30(54.5%)
Phase 2
21(38.2%)
N/A
3(5.5%)
Phase 1
1(1.8%)
55Total
Phase 3(30)
Phase 2(21)
N/A(3)
Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (55)

Showing 20 of 55 trials
NCT07214779Phase 3Recruiting

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Role: collaborator

NCT05659381Phase 3Recruiting

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

Role: lead

NCT06824467Phase 3Recruiting

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

Role: collaborator

NCT07023627Phase 2Recruiting

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Role: collaborator

NCT03786081Phase 1Terminated

Safety and Efficacy of Tisotumab Vedotin Monotherapy & in Combination With Other Cancer Agents in Subjects With Cervical Cancer

Role: collaborator

NCT06890338Phase 2Recruiting

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

Role: collaborator

NCT03555422Phase 3Completed

Maintenance With Selinexor/Placebo After Combination Chemotherapy in Participants With Endometrial Cancer [SIENDO]

Role: collaborator

NCT05446298Phase 2Active Not Recruiting

ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer

Role: collaborator

NCT06459180Phase 3Recruiting

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Role: collaborator

NCT07216703Phase 3Recruiting

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

Role: collaborator

NCT06072781Phase 3Recruiting

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Role: collaborator

NCT05649956Phase 2Recruiting

Letrozole in Uterine Leiomyosarcoma

Role: lead

NCT07024784Phase 2Recruiting

A Study to Assess Change in Disease Activity and Adverse Events in Adult Participants With Gynecologic Cancers Receiving Intravenous Infusion of IMGN151 as Monotherapy or in Combination With Other Therapies

Role: collaborator

NCT03894215Phase 2Terminated

RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer

Role: collaborator

NCT05548296Phase 2Recruiting

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

Role: collaborator

NCT07213804Phase 3Recruiting

A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

Role: collaborator

NCT07286266Phase 3Not Yet Recruiting

A Study to Investigate GSK5733584 Compared With Chemotherapy in Participants With Platinum-resistant Ovarian Cancer (BEHOLD-Ovarian01)

Role: collaborator

NCT05281471Phase 3Recruiting

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

Role: collaborator

NCT07286331Phase 3Not Yet Recruiting

A Study to Investigate GSK5733584 Compared With Chemotherapy in Participants With Recurrent Endometrial Cancer (BEHOLD-Endometrial01)

Role: collaborator

NCT04931342Phase 2Active Not Recruiting

A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors

Role: collaborator