Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

8.3%

1 terminated/withdrawn out of 12 trials

Success Rate

75.0%

-11.5% vs industry average

Late-Stage Pipeline

8%

1 trials in Phase 3/4

Results Transparency

0%

0 of 3 completed trials have results

Key Signals

5 recruiting

Enrollment Performance

Analytics

Phase 1
8(66.7%)
Phase 2
3(25.0%)
Phase 3
1(8.3%)
12Total
Phase 1(8)
Phase 2(3)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT07554859Phase 2Not Yet Recruiting

GFH375 Monotherapy and Combination Therapy as First-Line Treatment for Advanced KRAS G12D-Mutant Non-Small Cell Lung Cancer

Role: lead

NCT07262567Phase 3Not Yet Recruiting

Phase III Study to Compare GFH375 and Chemotherapy in Patients With KRAS G12D-Mutant Metastatic Pancreatic Cancer

Role: lead

NCT07259590Phase 1Recruiting

A Study of GFH375 Combined With Cetuximab or Chemotherapy in Participants With Solid Tumors Harboring KRAS G12D Mutation

Role: lead

NCT06500676Phase 1Recruiting

A Study of GFH375 in Patients With Advanced Solid Tumors With KRAS G12D Mutations

Role: lead

NCT07026916Phase 2Withdrawn

A Phase II Study to Evaluate GFH375 in Patients With KRAS G12D Mutant Metastatic Pancreatic Cancer

Role: lead

NCT05386888Phase 2Completed

A Trial of GFH018 and Toripalimab in Combination With Concurrent Chemoradiotherapy in Stage III NSCLC Chemoradiotherapy in Stage III NSCLC

Role: lead

NCT07198321Phase 1Not Yet Recruiting

A Single-Arm, Open-Label, Multicenter Phase I/II Clinical Study of GFH276 in Patients With RAS-Mutant Advanced Solid Tumors

Role: lead

NCT05756153Phase 1Completed

A Study of GFH925 in Combination With Cetuximab in Previously Untreated Advanced NSCLC Harboring KRAS G12C Mutation

Role: lead

NCT06375733Phase 1Recruiting

A Study of GFH009 in Combination With Zanubrutinib in Subjects With Relapsed or Refractory DLBCL

Role: lead

NCT06898255Phase 1Recruiting

A Phase I Study to Evaluate GFS202A in Advanced Solid Tumor Patients With Pre-cachexia or Cachexia

Role: lead

NCT04914286Phase 1Completed

A Study of GFH018 in Combination With Toripalimab in Patients With Advanced Solid Tumors

Role: lead

NCT05934513Phase 1Recruiting

A Study of GFH009 Monotherapy in Patients with Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

Role: lead

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