Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 90/100

Failure Rate

33.3%

4 terminated/withdrawn out of 12 trials

Success Rate

66.7%

-19.8% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

38%

3 of 8 completed trials have results

Key Signals

3 with results

Enrollment Performance

Analytics

Phase 2
7(58.3%)
Phase 1
5(41.7%)
12Total
Phase 2(7)
Phase 1(5)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT04365868Phase 2Terminated

Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

Role: lead

NCT02575404Phase 1Completed

GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer Patients

Role: collaborator

NCT04332432Phase 1Completed

A Single-dose, Open-label, Pharmacokinetic Study of Belapectin (GR-MD-02) in Subjects With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment

Role: lead

NCT02421094Phase 2Completed

Clinical Trial to Evaluate Efficacy of GR-MD-02 for Treatment of Liver Fibrosis in Patients With NASH With Advanced Fibrosis

Role: lead

NCT02462967Phase 2Completed

Clinical Trial to Evaluation the Safety and Efficacy of GR-MD-02 for the Treatment of Liver Fibrosis and Resultant Portal Hypertension in Patients With Nash Cirrhosis

Role: lead

NCT02407041Phase 2Completed

An Open-Label, Phase 2a Study to Evaluate Safety and Efficacy of GR-MD-02 for Treatment of Psoriasis

Role: lead

NCT02117362Phase 1Completed

Galectin Inhibitor (GR-MD-02) and Ipilimumab in Patients With Metastatic Melanoma

Role: collaborator

NCT00388700Phase 2Withdrawn

A New Agent GM-CT-01 in Combination With 5-FU, Avastin and Leucovorin in Subjects With Colorectal Cancer

Role: lead

NCT00386516Phase 2Withdrawn

Study to Test the Benefit and Safety of GM-CT-01 in Combination With 5-FU to Treat Bile Duct and Gall Bladder Cancer

Role: lead

NCT01899859Phase 1Completed

Phase 1 Study to Evaluate Safety of GR-MD-02 in Subjects With Non-Alcoholic Steatohepatitis (NASH) and Advanced Fibrosis

Role: lead

NCT00054977Phase 1Completed

Safety of GM-CT-01 With and Without 5-Fluorouracil in Patients With Solid Tumors

Role: lead

NCT00110721Phase 2Terminated

GM-CT-01 Plus 5-Fluorouracil as Third- or Fourth-Line Therapy for Metastatic Colorectal Cancer

Role: lead

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