Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

16.7%

2 terminated/withdrawn out of 12 trials

Success Rate

81.8%

-4.7% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

22%

2 of 9 completed trials have results

Key Signals

1 recruiting2 with results

Enrollment Performance

Analytics

Phase 1
7(58.3%)
Phase 2
5(41.7%)
12Total
Phase 1(7)
Phase 2(5)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT06939816Phase 2Terminated

Vonafexor in Patients With Impaired Renal Function and Suspected MASH (Metabolic Dysfunction-associated Steatohepatitis)

Role: lead

NCT07251153Phase 1Recruiting

Pharmacokinetic Comparison of Vonafexor Acid and Its Lysine Salt and Evaluation of Potential Drug-Drug Interactions

Role: lead

NCT06425055Phase 2Completed

Vonafexor ALPort Syndrome Efficacy & Safety TRIAl-1 (ALPESTRIA-1)

Role: lead

NCT03812029Phase 2Completed

Safety, Tolerability, Pharmacokinetics and Efficacy of EYP001a in Patients With Nonalcoholic Steatohepatitis (NASH)

Role: lead

NCT04465916Phase 2Terminated

Study of EYP001a to Assess Its Safety and Anti-viral Effect in CHB Patients in Combination With NA (ETV or TD)

Role: lead

NCT04365933Phase 2Completed

A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With Entecavir

Role: lead

NCT03976687Phase 1Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EYP001a in Healthy Volunteers and Nonalcoholic Steatohepatitis Patients

Role: lead

NCT04037618Phase 1Completed

Mass Balance Study to Investigate the Absorption, Metabolism and Excretion of [14C]-EYP001a After a Single Oral Dose

Role: lead

NCT03272009Phase 1Completed

Evaluation of the Safety and Pharmacology of EYP001 in HBV Subjects

Role: lead

NCT03469583Phase 1Completed

Drug Drug Interaction Study for EYP001 With Entecavir

Role: lead

NCT03320616Phase 1Completed

EYP001a Food Effect Study in Subjects With Chronic Hepatitis B Virus (HBV) Infection

Role: lead

NCT03110276Phase 1Completed

Study Evaluating Safety, Tolerability and Pharmacokinetics of EYP001a in Healthy Male Subjects

Role: lead

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