Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

33.7%

31 terminated/withdrawn out of 92 trials

Success Rate

56.3%

-30.2% vs industry average

Late-Stage Pipeline

22%

20 trials in Phase 3/4

Results Transparency

148%

59 of 40 completed trials have results

Key Signals

10 recruiting59 with results27 terminated4 withdrawn

Enrollment Performance

Analytics

Phase 1
42(48.8%)
Phase 2
24(27.9%)
Phase 3
19(22.1%)
Phase 4
1(1.2%)
86Total
Phase 1(42)
Phase 2(24)
Phase 3(19)
Phase 4(1)

Activity Timeline

Global Presence

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Clinical Trials (92)

Showing 20 of 92 trials
NCT07332481Phase 3Recruiting

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease

Role: lead

NCT05376891Recruiting

Met Non Small Cell Cancer Registry (MOMENT)

Role: lead

NCT06641908Phase 1Recruiting

Anti-GD2 ADC M3554 in Advanced Solid Tumors

Role: lead

NCT07549412Phase 3Recruiting

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

Role: lead

NCT04170153Phase 1Active Not Recruiting

Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)

Role: lead

NCT04457778Phase 1Completed

First in Human Study of M6223

Role: lead

NCT05081180Phase 1Active Not Recruiting

Study of Avelumab in Combination With Lenvatinib for Children With Primary CNS Tumors

Role: lead

NCT06710132Phase 1Recruiting

Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)

Role: lead

NCT07355218Phase 3Recruiting

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)

Role: lead

NCT07166601Phase 1Recruiting

M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors

Role: lead

NCT05327530Phase 2Active Not Recruiting

A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)

Role: lead

NCT05464030Phase 1Recruiting

Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)

Role: lead

NCT05198349Phase 1Terminated

First in Human Study of M1069 in Advanced Solid Tumors

Role: lead

NCT06463587Phase 3Recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Role: collaborator

NCT07360314Phase 1Recruiting

Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

Role: lead

NCT02864992Phase 2Active Not Recruiting

Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)

Role: lead

NCT03815643Phase 3Active Not Recruiting

Avelumab Program Rollover Study

Role: lead

NCT06421935Phase 1Active Not Recruiting

M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)

Role: lead

NCT03940703Phase 2Active Not Recruiting

A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)

Role: lead

NCT07097259Phase 1Completed

A Study to Assess the Bioequivalence of Follitropin Alfa Solution in Pen and Follitropin Alfa Powder in Vial in Healthy Downregulated Male Participants

Role: lead