Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

34.0%

32 terminated/withdrawn out of 94 trials

Success Rate

57.9%

-28.7% vs industry average

Late-Stage Pipeline

22%

21 trials in Phase 3/4

Results Transparency

139%

61 of 44 completed trials have results

Key Signals

9 recruiting61 with results28 terminated4 withdrawn

Enrollment Performance

Analytics

Phase 1
42(48.3%)
Phase 2
24(27.6%)
Phase 3
20(23.0%)
Phase 4
1(1.1%)
87Total
Phase 1(42)
Phase 2(24)
Phase 3(20)
Phase 4(1)

Activity Timeline

Global Presence

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Clinical Trials (94)

Showing 20 of 94 trials
NCT05376891Recruiting

Met Non Small Cell Cancer Registry (MOMENT)

Role: lead

NCT07360314Phase 1Recruiting

Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

Role: lead

NCT07787247Recruiting

Feasibility of Remote Monitoring of Patients With Myasthenia Gravis

Role: collaborator

NCT05327530Phase 2Active Not Recruiting

A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)

Role: lead

NCT07840287Phase 3Not Yet Recruiting

A Long-Term Extension (LTE) Study Of Enpatoran In Cutaneous Manifestations Of Lupus With Or Without Systemic Disease [Elowen-LTE]

Role: lead

NCT06641908Phase 1Recruiting

Anti-GD2 ADC M3554 in Advanced Solid Tumors

Role: lead

NCT03815643Phase 3Active Not Recruiting

Avelumab Program Rollover Study

Role: lead

NCT06463587Phase 3Recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Role: collaborator

NCT05396833Phase 1Completed

Study of Tuvusertib (M1774) in Combination With DNA Damage Response Inhibitor or Immune Checkpoint Inhibitor (DDRiver Solid Tumors 320)

Role: lead

NCT05882734Phase 1Completed

Tuvusertib (M1774) in Combination With Cemiplimab in Participants With Non-Squamous NSCLC (DDRiver NSCLC 322)

Role: lead

NCT06433219Phase 2Completed

Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)

Role: lead

NCT07355218Phase 3Recruiting

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)

Role: lead

NCT07332481Phase 3Recruiting

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease

Role: lead

NCT06421935Phase 1Active Not Recruiting

M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)

Role: lead

NCT07166601Phase 1Recruiting

M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors

Role: lead

NCT07549412Phase 3Recruiting

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

Role: lead

NCT05650567Phase 2Terminated

Study of M5049 in DM and PM Participants (NEPTUNIA)

Role: lead

NCT03940703Phase 2Completed

A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2)

Role: lead

NCT04170153Phase 1Active Not Recruiting

Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)

Role: lead

NCT05464030Phase 1Active Not Recruiting

Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)

Role: lead