Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

34.4%

11 terminated/withdrawn out of 32 trials

Success Rate

63.3%

-23.2% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

100%

19 of 19 completed trials have results

Key Signals

2 recruiting19 with results7 terminated4 withdrawn

Enrollment Performance

Analytics

N/A
29(93.5%)
Phase 2
1(3.2%)
Phase 1
1(3.2%)
31Total
N/A(29)
Phase 2(1)
Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (32)

Showing 20 of 32 trials
NCT07523685Not ApplicableRecruiting

Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)

Role: collaborator

NCT04935697Not ApplicableCompleted

Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory Distress

Role: collaborator

NCT03869008Not ApplicableTerminated

Potential Benefit for Non Invasive Vagus Nerve Stimulation Using GammaCore in the Treatment of Raynaud's Phenomena.

Role: collaborator

NCT04050501Not ApplicableCompleted

Non-invasive Vagus Nerve Stimulation in Acute Ischemic Stroke

Role: collaborator

NCT05103566Not ApplicableRecruiting

Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage

Role: collaborator

NCT05165108Not ApplicableTerminated

Non-invasive Vagus Nerve Stimulation in the Treatment of Crohn's Disease - A Pilot Study

Role: collaborator

NCT04857281Not ApplicableCompleted

Non-invasive Vagal Nerve Stimulation (nVNS) for Symptomatic Exacerbation of Nausea in Patients With Gastroparesis and Related Disorders

Role: collaborator

NCT04382391Not ApplicableTerminated

Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms

Role: collaborator

NCT04143269Not ApplicableCompleted

Treatment of Complications to Diabetic Autonomic Neuropathy With Vagus Nerve Stimulation

Role: collaborator

NCT03357029Not ApplicableCompleted

Neuromodulation in Patients With Painful Chronic Pancreatitis

Role: collaborator

NCT03733431Not ApplicableCompleted

Non-invasive TRanscutaneous Cervical Vagus Nerve Stimulation as a Treatment for Acute Stroke; Safety and Feasibility Study

Role: collaborator

NCT02974959Phase 1Completed

Vagus Nerve Stimulation to Treat Moderate Traumatic Brain Injury

Role: collaborator

NCT03716505Not ApplicableCompleted

Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines

Role: lead

NCT04071743Not ApplicableWithdrawn

Study of Gammacore Sapphire for the Acute and Preventive Treatment of Post-Traumatic Headache (GAP-PTH)

Role: collaborator

NCT01792817Not ApplicableCompleted

Non-invasive Neurostimulation of the Vagus Nerve for the Treatment of Cluster Headache

Role: lead

NCT02378844Not ApplicableCompleted

A Randomized, Sham-controlled Study of gammaCore ® (nVNS) for Prevention of Episodic Migraine

Role: lead

NCT02686034Not ApplicableCompleted

RCT of Non-Invasive Vagus Nerve Stimulation (nVNS) With gammaCore®, for the Acute Treatment of Migraine Attacks

Role: lead

NCT03787238Not ApplicableWithdrawn

A Randomized, Multicenter, Study for the prEvention and Acute Treatment of Migraine (REAL)

Role: lead

NCT01910129Not ApplicableTerminated

Neurostimulation to the Vagus Nerve for the Reduction in Frequency of Seizures Associated With Epilepsy

Role: lead

NCT01612793Terminated

Vagus Nerve Stimulation for Management of Bronchoconstriction in Patients Hospitalized With COPD Exacerbations

Role: lead