Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 30/100

Failure Rate

14.3%

9 terminated/withdrawn out of 63 trials

Success Rate

85.0%

-1.5% vs industry average

Late-Stage Pipeline

35%

22 trials in Phase 3/4

Results Transparency

51%

26 of 51 completed trials have results

Key Signals

26 with results8 terminated

Enrollment Performance

Analytics

Phase 2
19(33.9%)
Phase 3
17(30.4%)
Phase 1
14(25.0%)
Phase 4
5(8.9%)
N/A
1(1.8%)
56Total
Phase 2(19)
Phase 3(17)
Phase 1(14)
Phase 4(5)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (63)

Showing 20 of 63 trials
NCT06043700Active Not Recruiting

A Community-Based Screening Program to Identify Participants at High Risk for Amyloid Pathology

Role: lead

NCT02678780Phase 2Completed

Lenvatinib Efficacy in Metastatic Neuroendocrine Tumors

Role: collaborator

NCT06191952Not ApplicableUnknown

Davos Alzheimer's Collaborative Healthcare System Preparedness to Increase Cognitive Assessment Rates for Older Adults

Role: collaborator

NCT04840927Phase 1Withdrawn

A Study to Evaluate the Relative Bioavailability of E7386 Following Oral Administration of Targeted Release (TR) Tablets Compared to an E7386 Immediate Release (IR) Tablet in Healthy Adult Participants

Role: lead

NCT05084560Phase 1Terminated

Development of AWZ1066S, a Small Molecule Anti-Wolbachia Candidate Macrofilaricide Drug

Role: collaborator

NCT05607537Phase 1Completed

A Study to Determine the Absolute Bioavailability and the Absorption, Metabolism, and Elimination Properties of Carbon-14 (14C)E7386 in Healthy Male Participants

Role: lead

NCT02769364Completed

Extended Treatment in Metastatic Breast Cancer With Eribulin

Role: lead

NCT02432274Phase 1Completed

Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma

Role: lead

NCT01618136Phase 1Completed

An Open-Label, Multicenter, Phase 1/2 Study of Poly(ADP-Ribose) Polymerase (PARP) Inhibitor E7449 as Single Agent in Subjects With Advanced Solid Tumors or With B-cell Malignancies and in Combination With Temozolomide (TMZ) or With Carboplatin and Paclitaxel in Subjects With Advanced Solid Tumors

Role: lead

NCT04252846Completed

A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalization or With Primary Generalized Tonic-Clonic Seizures Associated With Idiopathic Generalized Epilepsy

Role: lead

NCT01761266Phase 3Completed

A Multicenter, Open-Label, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib (E7080) Versus Sorafenib in First-line Treatment of Participants With Unresectable Hepatocellular Carcinoma

Role: lead

NCT00688376Phase 3Completed

Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairment Following Cancer Treatment

Role: collaborator

NCT00566501Phase 3Completed

Open-Label Extension Study of 23 mg Donepezil SR in Participants With Moderate to Severe Alzheimer's Disease

Role: collaborator

NCT01268527Phase 2Completed

A 12-Day Randomized, Blinded, Vehicle and Active Comparator-Controlled Study to Determine the Efficacy and Safety of Six Concentrations of Topical E6201 Gel in Subjects With Psoriasis Vulgaris

Role: lead

NCT04493255Phase 1Completed

A Study to Determine the Metabolism and Elimination of [14C]E7090 in Healthy Male Participants

Role: lead

NCT01323530Phase 1Completed

A Confirmation Study of Eribulin in Combination With Capecitabine

Role: lead

NCT04257604Completed

A Study of Perampanel as Add-on Therapy in Adult and Adolescent Participants With Focal Seizures

Role: lead

NCT00388726Phase 3Completed

E7389 Versus Treatment of Physician's Choice in Patients With Locally Recurrent or Metastatic Breast Cancer

Role: collaborator

NCT01945710Phase 1Completed

An Open-label, Multicenter, Multiple Dose, Phase 1 Study to Establish the Maximum Tolerated Dose of E7389 Liposomal Formulation in Patients With Solid Tumors

Role: lead

NCT00548509Phase 4Completed

The Effect of Vitamin K2 on Bone Turnover

Role: lead