Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

0.0%

0 terminated/withdrawn out of 18 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

11%

1 of 9 completed trials have results

Key Signals

2 recruiting1 with results

Enrollment Performance

Analytics

Phase 1
11(68.8%)
Phase 2
5(31.3%)
16Total
Phase 1(11)
Phase 2(5)

Activity Timeline

Global Presence

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Clinical Trials (18)

Showing 18 of 18 trials
NCT06066580Phase 2Enrolling By Invitation

Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy

Role: lead

NCT05291091Phase 2Active Not Recruiting

Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)

Role: lead

NCT07034768Phase 1Completed

A Study to Evaluate EDG-7500 in People With Renal Impairment

Role: lead

NCT07324616Phase 1Recruiting

A Study to Evaluate EDG-7500 in Adults With Hepatic Impairment

Role: lead

NCT07456059Phase 1Not Yet Recruiting

A Study to Evaluate EDG-7500 in Caucasian and Japanese Adults

Role: lead

NCT06347159Phase 2Active Not Recruiting

A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)

Role: lead

NCT05540860Phase 2Active Not Recruiting

A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX)

Role: lead

NCT06100887Phase 2Active Not Recruiting

Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscular Dystrophy Previously Treated With Gene Therapy

Role: lead

NCT07177066Phase 1Recruiting

A Study of EDG-15400 in Healthy Adults

Role: lead

NCT05160415Phase 1Completed

A Study of EDG-5506 in Adult Males With Becker Muscular Dystrophy

Role: lead

NCT05257473Active Not Recruiting

Defining Endpoints in Becker Muscular Dystrophy

Role: collaborator

NCT06738836Phase 1Completed

A Study to Evaluate the Absorption, Metabolism, And Excretion Of Orally Administered [14C]-EDG-7500

Role: lead

NCT06916897Phase 1Completed

A Study to Evaluate Effect of Verapamil and Food of Sevasemten in Healthy Volunteers

Role: lead

NCT06011317Phase 1Completed

A Study of EDG-7500 in Healthy Adults

Role: lead

NCT05730842Phase 1Completed

Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers

Role: lead

NCT04349566Completed

Fast Troponin as a Biomarker to Assess Exercise-induced Muscle Damage in Muscle Diseases

Role: collaborator

NCT05492734Phase 1Completed

A Study to Assess the Feasibility of Non-invasive Dried Blood Sampling

Role: lead

NCT04585464Phase 1Completed

A Study to Assess Safety, Tolerability, and PK of EDG-5506 in Healthy Volunteers and Becker Muscular Dystrophy Adults

Role: lead

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