Drugs for Neglected Diseases
73
4
5
52
Key Highlights
Risk & Performance
Pipeline Risk Assessment
Pipeline Risk Assessment
Based on historical performance
Moderate Risk
Score: 35/100
9.6%
7 terminated/withdrawn out of 73 trials
88.1%
+1.5% vs industry average
29%
21 trials in Phase 3/4
17%
9 of 52 completed trials have results
Key Signals
Enrollment Performance
Analytics
Activity Timeline
Global Presence
Clinical Trials (73)
Stop Transmission of Gambiense Human African Trypanosomiasis
Role: collaborator
A Clinical Trial to Investigate Efficacy, Safety and Pharmacokinetics (PK) of Two LXE408 Oral Regimens and Oral Miltefosine as Active Control in Participants Aged ≥ 18 Years Old With Localized Cutaneous Leishmaniasis in the Region of the Americas (AMR).
Role: lead
A Phase II, Multicentre, Randomized, Two-arm Blinded Study to Assess the Efficacy and Safety of Two LXE408 Regimens for Treatment of Patients With Primary Visceral Leishmaniasis
Role: lead
Pharmacokinetic, Efficacy, Safety and Tolerability Study of a Single Dose of Acoziborole in g-HAT Paediatric Patients
Role: lead
LXE408 for Treatment of Visceral Leishmaniasis in Ethiopia, a Proof of Concept Study
Role: lead
Efficacy and Safety of Acoziborole (SCYX-7158) in Patients With Human African Trypanosomiasis Due to T.b. Gambiense
Role: lead
Combination, Miltefosine Monotherapy for Cutaneous Leishmaniasis in New World
Role: lead
Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South Sudan
Role: collaborator
Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects
Role: lead
Fexinidazole in Human African Trypanosomiasis Due to T. b. Rhodesiense
Role: lead
Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any Stage
Role: lead
Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection
Role: collaborator
Mycetoma Retrospective Data Collection
Role: lead
Eumycetoma Long-term Post-Treatment Follow-Up Study
Role: lead
Proof-of-Concept Superiority Trial of Fosravuconazole Versus Itraconazole for Eumycetoma in Sudan
Role: lead
New Therapies and Biomarkers for Chagas Infection
Role: collaborator
Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s)
Role: collaborator
Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT)
Role: lead
Emodepside Phase II Trial for Treatment of Onchocerciasis
Role: lead
Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa
Role: lead