Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

7.2%

15 terminated/withdrawn out of 207 trials

Success Rate

90.4%

+3.8% vs industry average

Late-Stage Pipeline

11%

23 trials in Phase 3/4

Results Transparency

43%

60 of 141 completed trials have results

Key Signals

32 recruiting60 with results12 terminated

Enrollment Performance

Analytics

N/A

52(40.3%)

Phase 2

35(27.1%)

Phase 1

18(14.0%)

Phase 3

16(12.4%)

Phase 4

7(5.4%)

Early Phase 1

1(0.8%)

129Total

N/A(52)

Phase 2(35)

Phase 1(18)

Phase 3(16)

+2 more

Activity Timeline

Global Presence

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Clinical Trials (207)

Showing 20 of 207 trials

NCT04798014Completed

HERO-2: Home-Reported Outcomes With CFTR Modulator Therapy

Role: collaborator

NCT06654752Not ApplicableRecruiting

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

Role: collaborator

NCT02819856Phase 2Completed

SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity

Role: collaborator

NCT07275905Phase 1Recruiting

Bacteriophages for Adults With Cystic Fibrosis and Chronic Achromobacter Lung Infection

Role: collaborator

NCT07699302Not ApplicableNot Yet Recruiting

Clearance in Primary Ciliary Dyskinesia

Role: collaborator

NCT07696338Not ApplicableNot Yet Recruiting

Rethinking Early Airway Clearence Therapies

Role: collaborator

NCT04509050Recruiting

Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

Role: collaborator

NCT05548283Phase 4Recruiting

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

Role: collaborator

NCT07048574Recruiting

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

Role: collaborator

NCT07312734Recruiting

Study to Enable New Diagnostics for Pulmonary Microbes in People With CF

Role: collaborator

NCT06057714Recruiting

Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis

Role: collaborator

NCT06066723Recruiting

19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease

Role: collaborator

NCT06449677Phase 3Recruiting

Bionic Pancreas in CFRD

Role: collaborator

NCT06616857Not ApplicableRecruiting

Personalized Mobile Health Platform to Promote Physical Activity in Adolescents and Young Adults With Cystic Fibrosis

Role: collaborator

NCT05074680Completed

COVID-19 Antibody Responses In Cystic Fibrosis

Role: collaborator

NCT03161808Recruiting

Rare CFTR Mutation Cell Collection Protocol (RARE)

Role: collaborator

NCT04002882Recruiting

Role of Body Fat Distribution in Metabolic and Pulmonary Decline in Cystic Fibrosis (ORBIT-CF)

Role: collaborator

NCT00659529Phase 1Completed

Safety and Efficacy of Sildenafil in Cystic Fibrosis (CF) Lung Disease

Role: collaborator

NCT04310930Phase 2Recruiting

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment

Role: collaborator

NCT04613128Completed

The PROMISE Pediatric Study 6 to 11 Years Old

Role: collaborator