Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 90/100

Failure Rate

31.6%

6 terminated/withdrawn out of 19 trials

Success Rate

50.0%

-36.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

50%

3 of 6 completed trials have results

Key Signals

3 recruiting3 with results

Enrollment Performance

Analytics

Phase 2
9(50.0%)
Phase 1
8(44.4%)
N/A
1(5.6%)
18Total
Phase 2(9)
Phase 1(8)
N/A(1)

Activity Timeline

Global Presence

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Clinical Trials (19)

Showing 19 of 19 trials
NCT04791384Phase 1Terminated

Phase Ib/II Trial of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/Her2- Breast Cancer

Role: lead

NCT04963283Phase 2Active Not Recruiting

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

Role: collaborator

NCT06992258Phase 2Recruiting

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

Role: lead

NCT05230810Phase 1Active Not Recruiting

Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer.

Role: lead

NCT05458674Phase 2Recruiting

Tucatinib+Trastuzumab+Eribulin in HER2+ MBC

Role: lead

NCT04567420Phase 2Recruiting

DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)

Role: lead

NCT02723331Phase 2Completed

Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular Correlates

Role: collaborator

NCT03389399Completed

Pulmonary Physiology and Systemic Inflammatory in EO Pulmonary Events With Brigatinib Use in NSCLC and Other Diseases

Role: collaborator

NCT05167409Phase 2Active Not Recruiting

A Study of Evorpacept (ALX148) With Cetuximab and Pembrolizumab for Refractory Microsatellite Stable Metastatic Colorectal Cancer

Role: collaborator

NCT03054363Phase 1Completed

Tucatinib, Palbociclib and Letrozole in Metastatic Hormone Receptor Positive and HER2-positive Breast Cancer

Role: collaborator

NCT05180422Phase 1Withdrawn

A Phase I/II Study of AMG 510 in Combination With MVASI in Patients With Advanced, Unresectable or Metastatic KRAS G12C Mutant NSCLC With Asymptomatic Brain Metastasis

Role: lead

NCT04739358Phase 1Terminated

CNS Dose Escalation/Expansion of Tepotinib in MET-driven NSCLC

Role: lead

NCT04169347Phase 2Unknown

FOLFOXIRI Plus Panitumumab in Metastatic RAS Wild-type, Left-sided Colorectal Cancer

Role: lead

NCT02706626Phase 2Terminated

Trial of Brigatinib After Treatment With Next-Generation ALK Inhibitors

Role: lead

NCT01464034Phase 1Terminated

A Safety and Efficacy Study of Carfilzomib and Pomalidomide With Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

Role: lead

NCT02638909Phase 2Terminated

Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignancies

Role: lead

NCT01660750Phase 1Completed

A Safety Study of Carfilzomib, Cyclophosphamide & Dexamethasone Prior to ASCT in Patients With Newly Diagnosed Myeloma

Role: lead

NCT01789242Phase 1Completed

A Safety Study of Carfilzomib in Patients With Previously-Treated Systemic Light Chain Amyloidosis

Role: lead

NCT01654094Not ApplicableCompleted

Study of Low Adherent Dressing Versus the Standard of Care for the Management of Skin Grafts Over Thermal Burns

Role: collaborator

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